2-Amino-4-cyclohexylimino-4,5-dihydrothiazole Hydrochloride

Base Information

• Chemical Name: 2-Amino-4-cyclohexylimino-4,5-dihydrothiazole Hydrochloride
• CAS No.: 121721-57-1
• Molecular Formula: C₉H₁₅N₃S*ClH
• Molecular Weight: 233.765
• Mol file: 121721-57-1.mol

Synonyms:

Chemical Property of 2-Amino-4-cyclohexylimino-4,5-dihydrothiazole Hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Amino-4-cyclohexylimino-4,5-dihydrothiazole Hydrochloride

There total 3 articles about 2-Amino-4-cyclohexylimino-4,5-dihydrothiazole Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

N-(cyclohexyl)-N'-(p-toluenesulfonyl)-2-chloroacetamidine (121721-47-9) + thiourea (17356-08-0) → 2-Amino-4-cyclohexylimino-4,5-dihydrothiazole Hydrochloride (121721-57-1)

Guidance literature:

In butanone; for 0.5h; Heating;

Reference yield:

cyclohexylamine hydrochloride (4998-76-9) → 2-Amino-4-cyclohexylimino-4,5-dihydrothiazole Hydrochloride (121721-57-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 1) Na / 1) MeOH, 10 deg C, 1 h; 2) 0-10 deg C, 1 h

2: 52 percent / 10percent Na₂CO₃ / acetone / 0.25 h / Ambient temperature

3: 81 percent / butan-2-one / 0.5 h / Heating

With sodium; sodium carbonate; In acetone; butanone;

Reference yield:

N-(Cyclohexyl)-2-chloroacetamidine Hydrochloride (19412-46-5) → 2-Amino-4-cyclohexylimino-4,5-dihydrothiazole Hydrochloride (121721-57-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 52 percent / 10percent Na₂CO₃ / acetone / 0.25 h / Ambient temperature

2: 81 percent / butan-2-one / 0.5 h / Heating

With sodium carbonate; In acetone; butanone;

upstream raw materials:

N-(cyclohexyl)-N'-(p-toluenesulfonyl)-2-chloroacetamidine

thiourea

cyclohexylamine hydrochloride

N-(Cyclohexyl)-2-chloroacetamidine Hydrochloride

Refernces