Cyclohexylamine hydrochloride

Base Information

• Chemical Name: Cyclohexylamine hydrochloride
• CAS No.: 4998-76-9
• Molecular Formula: C6H13N^.HCl
• Molecular Weight: 135.637
• Hs Code.: 2921300090
• European Community (EC) Number: 225-661-4
• UNII: TN6VYF8THC
• Wikidata: Q27290044
• ChEMBL ID: CHEMBL3188904
• Mol file: 4998-76-9.mol

Synonyms:Cyclohexylamine hydrochloride;4998-76-9;cyclohexanamine hydrochloride;Cyclohexanamine, hydrochloride;Aminocyclohexane hydrochloride;Cyclohexylamine.HCl;MFCD00050540;Cyclohexanamine, hydrochloride (1:1);Aminohexahydrobenzene hydrochloride;CYCLOHEXYLAMINE, HYDROCHLORIDE;TN6VYF8THC;UNII-TN6VYF8THC;CYCLOHEXYLAMINE HCl;C6H13N.ClH;cyclohexanamine;hydrochloride;SCHEMBL960719;2-aminocyclohexane hydrochloride;CHEMBL3188904;ZJUGSKJHHWASAF-UHFFFAOYSA-N;98%;AKOS015894458;CS-W013335;AS-16076;3-METHYL-2-PHENYLAMINO-BENZOICACID;FT-0624219;EN300-29994;A871691;Q27290044;Z1945707495

Chemical Property of Cyclohexylamine hydrochloride

Chemical Property:

• Appearance/Colour: white to beige crystalline powder
• Vapor Pressure: 8.07mmHg at 25°C
• Melting Point: 207 °C
• Refractive Index: 1.4530 (estimate)
• Boiling Point: 134.5 °C at 760 mmHg
• Flash Point: 32.2 °C
• PSA: 26.02000
• Density: 4.7 （Vapor Density）
• LogP: 2.78010
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Water Solubility.: 83 g/100 mL (17 ºC)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 135.0814771
• Heavy Atom Count: 8
• Complexity: 46.1

Purity/Quality:

99% ^*data from raw suppliers

Cyclohexylamine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,Xn
• Hazard Codes: Xn,Xi
• Statements: 36/37/38-20/21/22-41-37/38-22
• Safety Statements: 36/37/39-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CCC(CC1)N.Cl

Technology Process of Cyclohexylamine hydrochloride

There total 51 articles about Cyclohexylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclohexylamine (108-91-8,157973-60-9) → cyclohexylamine hydrochloride (4998-76-9)

Guidance literature:

With hydroxylamine hydrochloride; In ethanol; for 2h; Reflux;

DOI:10.1080/00397911.2015.1096943

Reference yield: 99.0%

1-nitrocyclohexane (1122-60-7) → cyclohexylamine hydrochloride (4998-76-9)

Guidance literature:

1-nitrocyclohexane; With iron(III)-acetylacetonate; hydrazine hydrate; In methanol; at 150 ℃; for 0.0333333h; Microwave irradiation;

With hydrogenchloride; In water; ethyl acetate; chemoselective reaction;

DOI:10.1021/jo400556g

Reference yield: 96.0%

anthracene (120-12-7) + cyclohexylamine (108-91-8,157973-60-9) → 9,10-dichloroanthracene (605-48-1) + cyclohexylamine hydrochloride (4998-76-9)

Guidance literature:

With chloroform; oxygen; sodium hydrogencarbonate; triethylamine; In methanol; water; for 1.5h; Irradiation;

DOI:10.1021/ol301356r

upstream raw materials:

tetrachloromethane

methyl phosphite

cyclohexylamine

cyclohexanone-oxime

Downstream raw materials:

cyclohexyl-(5-methyl-furfuryl)-amine

Cyclohexyl isocyanate

N⁴-cyclohexyl-pyrimidine-4,6-diyldiamine

4-(cyclohexylamino)pyridine

Refernces

• 1、 -. "Green method for catalyzing reduction reaction of aliphatic nitro derivative". Paragraph 0005-0006; 0045-0048. . Retrieved 2021/07/31.
• 2、 -. "Method for preparing amine compound by reducing amide compound". Paragraph 0253-0255. . Retrieved 2021/02/10.