(2S^*,3R^*)-2-hydroxy-3-phenylbutyric acid ethyl ester

Base Information

• Chemical Name: (2S^*,3R^*)-2-hydroxy-3-phenylbutyric acid ethyl ester
• CAS No.: 36076-17-2
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.257
• Mol file: 36076-17-2.mol

Synonyms:

Chemical Property of (2S^*,3R^*)-2-hydroxy-3-phenylbutyric acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S^*,3R^*)-2-hydroxy-3-phenylbutyric acid ethyl ester

There total 7 articles about (2S^*,3R^*)-2-hydroxy-3-phenylbutyric acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fraeseol (77-83-8) → (2S,3S)-2-Hydroxy-3-phenyl-butyric acid ethyl ester (36076-17-2,36076-18-3) + (2S*,3R*)-2-hydroxy-3-phenylbutyric acid ethyl ester (36076-17-2,36076-18-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In hexane; under 1875.1 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

Reference yield:

fraeseol (77-83-8) → (2S,3S)-2-Hydroxy-3-phenyl-butyric acid ethyl ester (36076-17-2,36076-18-3) + (2S*,3R*)-2-hydroxy-3-phenylbutyric acid ethyl ester (36076-17-2,36076-18-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In hexane; under 1875.1 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

Reference yield:

fraeseol (77-83-8) → erythro-3-Phenyl-2-hydroxy-buttersaeure-ethylester (36076-17-2,36076-18-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / hexane / 1875.1 Torr

With hydrogen; palladium on activated charcoal; In hexane;

upstream raw materials:

(2S^*,3R^*)-2-hydroxy-3-phenylbutyric acid ethyl ester

fraeseol

ethyl 3-phenylbutanoate

Downstream raw materials:

erythro-3-Phenyl-2-hydroxy-buttersaeure-ethylester

Refernces

• 1、 Morizawa, Yoshitomi,Yasuda, Arata,Uchida, Keiichi. "TRIFLUOROMETHYL GROUP INDUCED HIGHLY STEREOSELECTIVE SYNTHESIS OF α-HYDROXY CARBONYL COMPOUNDS". . p. 1833 - 1836. Retrieved 2007/10/02.