Technology Process of 12-Benzenesulfonyl-7-hydroxy-6,12-dihydro-7H-indolo[2,3-a]quinolizin-5-ylium; bromide
There total 4 articles about 12-Benzenesulfonyl-7-hydroxy-6,12-dihydro-7H-indolo[2,3-a]quinolizin-5-ylium; bromide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 63 percent / tetrahydrofuran / 8 h / -78 degC then allowed to reach room temperature
2: 73 percent / NaH / tetrahydrofuran / 0 °C
3: 1.) n-butyllithium; 2.) HOAc / 1.) THF
With
n-butyllithium; sodium hydride; acetic acid;
In
tetrahydrofuran;
DOI:10.1016/S0040-4039(00)96702-9
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 73 percent / NaH / tetrahydrofuran / 0 °C
2: 1.) n-butyllithium; 2.) HOAc / 1.) THF
With
n-butyllithium; sodium hydride; acetic acid;
In
tetrahydrofuran;
DOI:10.1016/S0040-4039(00)96702-9
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 63 percent / tetrahydrofuran / 8 h / -78 degC then allowed to reach room temperature
2: 73 percent / NaH / tetrahydrofuran / 0 °C
3: 1.) n-butyllithium; 2.) HOAc / 1.) THF
With
n-butyllithium; sodium hydride; acetic acid;
In
tetrahydrofuran;
DOI:10.1016/S0040-4039(00)96702-9
