Dicyclohexyl(tetrahydropyranyl-2-methyl)phosphan

Base Information

• Chemical Name: Dicyclohexyl(tetrahydropyranyl-2-methyl)phosphan
• CAS No.: 135492-10-3
• Molecular Formula: C₁₈H₃₃OP
• Molecular Weight: 296.433
• Mol file: 135492-10-3.mol

Synonyms:

Chemical Property of Dicyclohexyl(tetrahydropyranyl-2-methyl)phosphan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dicyclohexyl(tetrahydropyranyl-2-methyl)phosphan

There total 1 articles about Dicyclohexyl(tetrahydropyranyl-2-methyl)phosphan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(chloromethyl)tetrahydropyran (18420-41-2,130233-13-5,130233-14-6) + dicyclohexylphosphane (829-84-5) → Dicyclohexyl(tetrahydropyranyl-2-methyl)phosphan (135492-10-3)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1) THF, n-hexane, a) 0 deg C to 20 deg C, b) 20 deg C, 0.5 h, 2) reflux, 15 min;

Reference yield: 72.1%

dichloro(1,5-cyclooctadiene)platinum(ll) (12080-32-9) + Dicyclohexyl(tetrahydropyranyl-2-methyl)phosphan (135492-10-3) → trans-dichlorobis{dicyclohexyl(tetrahydropyranyl-2-methyl)phosphane-P}platinum(II) (135483-97-5)

Guidance literature:

In dichloromethane; byproducts: 1,5-cyclooctadiene; under Ar, addn. of soln. of phosphane to soln. of complex within 0.5 h, stirring for 2 h; evapn. of solvent in vac., stirring of residue in Et2O-pentane overnight, centrifugation, sepn. of powder, drying in vac., elem. anal.;

Reference yield: 69.5%

dichloro(cycloocta-1,5-diene)palladium (II) (12107-56-1) + Dicyclohexyl(tetrahydropyranyl-2-methyl)phosphan (135492-10-3) → trans-dichlorobis{dicyclohexyl(tetrahydropyranyl-2-methyl)phosphane-P}palladium(II) (135483-94-2,135558-32-6)

Guidance literature:

In dichloromethane; byproducts: 1,5-cyclooctadiene; under Ar, addn. of soln. of phosphane to soln. of complex within 0.5 h, stirring for 2 h; evapn. of solvent in vac., stirring of residue in cold acetone for 0.5 h, centrifugation, sepn. of powder, elem. anal.;

upstream raw materials:

2-(chloromethyl)tetrahydropyran

dicyclohexylphosphane

Downstream raw materials:

cis-dichlorobis{dicyclohexyl(tetrahydropyranyl-2-methyl)phosphane-P}palladium(II)

trans-dichlorobis{dicyclohexyl(tetrahydropyranyl-2-methyl)phosphane-P}palladium(II)

trans-dichlorobis{dicyclohexyl(tetrahydropyranyl-2-methyl)phosphane-P}platinum(II)

trans-chlorobis{dicyclohexyl(tetrahydropyranyl-2-methyl)phosphane-P;O',P'}palladium(II) perchlorate

Refernces