3-fluorooxaloacetate

Base Information

• Chemical Name: 3-fluorooxaloacetate
• CAS No.: 392-47-2
• Molecular Formula: C4H3 F O5
• Molecular Weight: 150.063
• Hs Code.: 2918300090
• Mol file: 392-47-2.mol

Synonyms:Butanedioicacid, fluorooxo- (9CI); Oxalacetic acid, fluoro- (6CI,7CI,8CI);Fluorooxalacetic acid; Monofluorooxalacetic acid

Chemical Property of 3-fluorooxaloacetate

Chemical Property:

• Vapor Pressure: 3.74E-05mmHg at 25°C
• Boiling Point: 328.5°Cat760mmHg
• Flash Point: 152.4°C
• PSA: 91.67000
• Density: 1.729g/cm³
• LogP: -0.93720

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-fluorooxaloacetate

There total 9 articles about 3-fluorooxaloacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4,5,6-pentafluorophenol (771-61-9) → difluoromaleic acid (685-64-3,2714-32-1,26180-09-6) + carbon dioxide (124-38-9,18923-20-1) + carbon monoxide (201230-82-2) + monofluoro-oxaloacetate (392-47-2) + oxalic acid (144-62-7,97993-78-7)

Guidance literature:

With dihydrogen peroxide; In water; at 60 ℃; for 15h; Solvent; Reagent/catalyst; Catalytic behavior; Inert atmosphere;

DOI:10.1021/ja505437h

Reference yield:

Diethyl fluoroxaloacetate (392-58-5) → fluoropyruvic acid (433-48-7) + monofluoro-oxaloacetate (392-47-2)

Guidance literature:

With hydrogenchloride; acetic acid; at 5 ℃; for 600h; Yields of byproduct given;

Reference yield:

pentafluorobenzenesulfonic acid (313-50-8) → difluoromaleic acid (685-64-3,2714-32-1,26180-09-6) + monofluoro-oxaloacetate (392-47-2)

Guidance literature:

With dihydrogen peroxide; In water; at 60 ℃; for 15h; Catalytic behavior;

DOI:10.1021/ja505437h

upstream raw materials:

Diethyl fluoroxaloacetate

ethyl 2-fluoroacetate

oxalic acid diethyl ester

pentafluorobenzenesulfonic acid

Refernces

• 1、 Brandaenge, Svante,Dahlman, Olof,Mahlen, Anders,Moerch, Lars. "Stereoselectivities in Enzymatic Syntheses of Fluorocitric Acid". . p. 67 - 70. Retrieved 2007/10/02.
• 2、 Dummel,Berry,Kun. "Studies with specific enzyme inhibitors. 13. Kinetics of nonenzymatic decarboxylation of fluorooxalacetic acid.". . p. 367 - 374. Retrieved 2007/10/14.