1α,3α-Cyclopentanediol

Base Information

• Chemical Name: 1α,3α-Cyclopentanediol
• CAS No.: 16326-97-9
• Molecular Formula: C5H10 O2
• Molecular Weight: 102.133
• Hs Code.: 2906199090
• Mol file: 16326-97-9.mol

Synonyms:1,3-Cyclopentanediol,cis- (8CI); cis-1,3-Cyclopentanediol

Chemical Property of 1α,3α-Cyclopentanediol

Chemical Property:

• Melting Point: 31°C
• Refractive Index: 1.4792 (estimate)
• Boiling Point: 151.45°C (rough estimate)
• PKA: 14.65±0.40(Predicted)
• PSA: 40.46000
• Density: 1.0990
• LogP: -0.10790

Purity/Quality:

99% ^*data from raw suppliers

cis-cyclopentane-1,3-diol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1α,3α-Cyclopentanediol

There total 45 articles about 1α,3α-Cyclopentanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-Hydroxycyclopent-2-enone (59995-47-0,59995-49-2,61305-27-9,61740-29-2) → 1,3-dihydroxycyclopentane (16326-97-9,16326-98-0,59719-74-3)

Guidance literature:

In tetrahydrofuran; at 160 ℃; for 1h; Reagent/catalyst; Temperature; Solvent; Concentration;

Reference yield: 69.0%

1,3-cyclopentadione (3859-41-4) → 1,3-dihydroxycyclopentane (16326-97-9,16326-98-0,59719-74-3)

Guidance literature:

With hydrogen; isopropyl alcohol; ruthenium-based catalyst; In toluene; at 80 ℃; for 48h;

DOI:10.1021/jo0612527

Reference yield: 41.0%

1,3-epiperoxycyclopentane (279-35-6) → 4,5-epoxypentanal (65842-25-3) + ethene (74-85-1) + cis-cyclopentane-1,3-diol (16326-97-9)

Guidance literature:

With cobalt(II) 5,10,15,20-tetraphenylporphyrin; In chloroform; at 40 ℃; for 14h; Product distribution; Mechanism; various saturated bicyclic endoperoxides; investigation of the influence of the ring size and reaction conditions on the CoTPP catalyzed decomposition pathway;

DOI:10.1016/S0040-4020(01)96533-0

upstream raw materials:

cis-4-cyclopentene-1,3-diol

6-oxabicyclo[3.1.0]hex-2-ene

1,3-epiperoxycyclopentane

rac-3-hydroxycyclopentanone

Downstream raw materials:

trans-1,3-cyclopentanediol

3-hydroxycyclopentyl 4-methylbenzenesulfonate

bi(cyclopentadiene)

cyclopenta-1,3-diene

Refernces

• 1、 Korach et al.. "-". . p. 4328. Retrieved 1960.
• 2、 Saegebarth. "". . p. 2212,2213. Retrieved 1960.
• 3、 Macmillan, David W. C.,Oswood, Christian J.. "Selective Isomerization via Transient Thermodynamic Control: Dynamic Epimerization of trans to cis Diols". supporting information. p. 93 - 98. Retrieved 2022/01/03.
• 4、 -. "Application of hierarchical pore molecular sieve in preparation process of cyclopentadiene and JP-10 aviation fuel". Paragraph 0023; 0087-0104. . Retrieved 2021/07/01.