6-Acetyl-10-hydroxycodeine

Base Information

• Chemical Name: 6-Acetyl-10-hydroxycodeine
• CAS No.: 96562-81-1
• Molecular Formula: C₂₀H₂₃NO₅
• Molecular Weight: 357.406
• Mol file: 96562-81-1.mol

Synonyms:

Chemical Property of 6-Acetyl-10-hydroxycodeine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-Acetyl-10-hydroxycodeine

There total 1 articles about 6-Acetyl-10-hydroxycodeine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-acetylcodeine (6703-27-1) → 6-Acetyl-10-oxocodeine (96562-83-3) + 6-Acetyl-10-hydroxycodeine (96562-81-1)

Guidance literature:

With potassium dichromate; sulfuric acid; In water; at 5 ℃; for 3h;

Reference yield:

6-Acetyl-10-hydroxycodeine (96562-81-1) → 10-Oxomorphine (68254-48-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 210 mg / MnO₂ / CHCl₃ / 17 h

2: 70 mg / 1 M aq. HCl / 3 h / 90 °C

3: 9 mg / conc. HBr / 0.33 h / 110 - 120 °C

With hydrogenchloride; manganese(IV) oxide; hydrogen bromide; In chloroform;

Reference yield:

6-Acetyl-10-hydroxycodeine (96562-81-1) → 6-Acetyl-10-oxocodeine (96562-83-3)

Guidance literature:

With manganese(IV) oxide; In chloroform; for 17h;

upstream raw materials:

6-acetylcodeine

Downstream raw materials:

6-Acetyl-10-oxocodeine

10-Oxomorphine

Refernces