1-(2,6-diisopropylphenyl)-3-[ (6-{[N-methyl-3-(triethoxysilyl)propan-1-amino]methyl}pyridin-2-yl)methyl]-1H-imidazol-3-ium bromide

Base Information

• Chemical Name: 1-(2,6-diisopropylphenyl)-3-[ (6-{[N-methyl-3-(triethoxysilyl)propan-1-amino]methyl}pyridin-2-yl)methyl]-1H-imidazol-3-ium bromide
• CAS No.: 1288927-14-9
• Molecular Formula: Br*C₃₂H₅₁N₄O₃Si
• Molecular Weight: 647.771
• Mol file: 1288927-14-9.mol

Synonyms:

Chemical Property of 1-(2,6-diisopropylphenyl)-3-[ (6-{[N-methyl-3-(triethoxysilyl)propan-1-amino]methyl}pyridin-2-yl)methyl]-1H-imidazol-3-ium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2,6-diisopropylphenyl)-3-[ (6-{[N-methyl-3-(triethoxysilyl)propan-1-amino]methyl}pyridin-2-yl)methyl]-1H-imidazol-3-ium bromide

There total 2 articles about 1-(2,6-diisopropylphenyl)-3-[ (6-{[N-methyl-3-(triethoxysilyl)propan-1-amino]methyl}pyridin-2-yl)methyl]-1H-imidazol-3-ium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-bis-(bromomethyl)pyridine (7703-74-4) + 1-(2,6-diisopropylphenyl)-1H-imidazole (25364-47-0) → 1-(2,6-diisopropylphenyl)-3-[ (6-{[N-methyl-3-(triethoxysilyl)propan-1-amino]methyl}pyridin-2-yl)methyl]-1H-imidazol-3-ium bromide (1288927-14-9)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 18 h / Reflux

2: acetone / Alkaline conditions

In acetone;

DOI:10.1021/om101179a

Reference yield:

N-methyl-3-(triethoxysilyl)propan-1-amine (6044-50-4) + 3-{[6-(bromomethyl)pyridin-2-yl]methyl}-1-(2,6-diisopropylphenyl)-1H-imidazol-3-ium bromide (1203477-58-0) → 1-(2,6-diisopropylphenyl)-3-[ (6-{[N-methyl-3-(triethoxysilyl)propan-1-amino]methyl}pyridin-2-yl)methyl]-1H-imidazol-3-ium bromide (1288927-14-9)

Guidance literature:

In acetone; Alkaline conditions;

DOI:10.1021/om101179a

Reference yield:

(carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II) (157072-60-1,61521-25-3,166941-05-5,16971-33-8) + 1-(2,6-diisopropylphenyl)-3-[ (6-{[N-methyl-3-(triethoxysilyl)propan-1-amino]methyl}pyridin-2-yl)methyl]-1H-imidazol-3-ium bromide (1288927-14-9) → [Ru(H)Cl(CO)(2-[[3-(2,6-diisopropylphenyl)-2,3-dihydro-1H-imidazol-1-yl]methyl]-6-[[N-methyl-3-(triethoxysilyl)propan-1-amino]methyl]pyridine)]

Guidance literature:

With Ag₂O; In dichloromethane; byproducts: AgCl; under Ar and light-free conditions; imidazolium salt dissolved in CH2Cl2; Ag2O added; stirred at room temp. for 24 h; filtered through Celite; Ru complex in CH2Cl2 added to filtrate; stirred at room temp. overnight; filtered in air; solvent removed in vac.; triturated with Et2O; elem. anal.;

DOI:10.1021/om101179a

upstream raw materials:

2,6-bis-(bromomethyl)pyridine

1-(2,6-diisopropylphenyl)-1H-imidazole

N-methyl-3-(triethoxysilyl)propan-1-amine

3-{[6-(bromomethyl)pyridin-2-yl]methyl}-1-(2,6-diisopropylphenyl)-1H-imidazol-3-ium bromide

Refernces