2-Amino-4-isopropyl-3-cyan-thiophen

Base Information

• Chemical Name: 2-Amino-4-isopropyl-3-cyan-thiophen
• CAS No.: 10413-35-1
• Molecular Formula: C₈H₁₀N₂S
• Molecular Weight: 166.247
• Hs Code.: 2934999090
• Mol file: 10413-35-1.mol

Synonyms:

Chemical Property of 2-Amino-4-isopropyl-3-cyan-thiophen

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Amino-4-isopropylthiophene-3-carbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-amino-4-isopropylthiophene-3-carbonitrile is a versatile building block that can be prepared by ultrasound-mediated Gewald reaction of sulfur with dinitriles and sodium polysulfide.

Technology Process of 2-Amino-4-isopropyl-3-cyan-thiophen

There total 2 articles about 2-Amino-4-isopropyl-3-cyan-thiophen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

isobutyraldehyde (78-84-2) + malononitrile (109-77-3) → 2-Amino-4-isopropyl-3-cyan-thiophen (10413-35-1)

Guidance literature:

isobutyraldehyde; malononitrile; In water; for 0.333333h; Sonication; Green chemistry;

With Na₂S₆; In water; for 0.5h; Sonication; Green chemistry;

DOI:10.1080/17415993.2012.754892

Reference yield:

→ 2-Amino-4-isopropyl-3-cyan-thiophen (10413-35-1)

Guidance literature:

3-Isorpopyl-2-cyan-crotonsaeure-nitril, Schwefel/Et2NH/absol. A. (20grad);

upstream raw materials:

isobutyraldehyde

malononitrile

Refernces