trans-2-hydroxy-3-thujene

Base Information

• Chemical Name: trans-2-hydroxy-3-thujene
• CAS No.: 7766-03-2
• Molecular Formula: C₁₀H₁₆O
• Molecular Weight: 152.236
• Mol file: 7766-03-2.mol

Synonyms:

Chemical Property of trans-2-hydroxy-3-thujene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-2-hydroxy-3-thujene

There total 4 articles about trans-2-hydroxy-3-thujene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

α-thujene (563-34-8,2867-05-2,3917-48-4,75715-79-6) → trans-2-hydroxy-3-thujene (7766-03-2,97631-68-0)

Guidance literature:

With oxygen; Rose Bengal lactone; In methanol; Irradiation;

DOI:10.1016/0040-4020(66)80132-1

Reference yield:

(-)-3-thujol (21653-20-3) → trans-2-hydroxy-3-thujene (7766-03-2,97631-68-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / Et₃N / diethyl ether / 3 h / 0 °C

2: 1.) 18-crown-6, KOH, 2.) TBA-BH₄, Rose Bengal, O₂ / 1.) toluene, 100 deg C, 4 h, 2.) CHCl₃, irrad., 60 min

With potassium hydroxide; 18-crown-6 ether; oxygen; rose bengal; tetrabutylammonium borohydride; triethylamine; In diethyl ether;

DOI:10.1016/0968-0896(96)00020-X

Reference yield:

trans-sabinyl acetate (53833-85-5) → trans-2-hydroxy-3-thujene (7766-03-2,97631-68-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Na, liq. NH₃ / diethyl ether

2: O₂, bengal red / methanol / Irradiation

With ammonia; oxygen; sodium; Rose Bengal lactone; In methanol; diethyl ether;

DOI:10.1016/0040-4020(66)80132-1

upstream raw materials:

α-thujene

Methanesulfonic acid (1S,3S,4R,5R)-1-isopropyl-4-methyl-bicyclo[3.1.0]hex-3-yl ester

(-)-3-thujol

trans-sabinyl acetate

Refernces