4-Hydroxyamiodarone

Base Information

• Chemical Name: 4-Hydroxyamiodarone
• CAS No.: 1355969-25-3
• Molecular Formula: C₂₅H₂₉I₂NO₄
• Molecular Weight: 661.319
• Mol file: 1355969-25-3.mol

Synonyms:

Chemical Property of 4-Hydroxyamiodarone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 4-Hydroxyamiodarone

There total 1 articles about 4-Hydroxyamiodarone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

amiodarone hydrochloride (19774-82-4) → 4-Hydroxyamiodarone (1355969-25-3) + (+/-)-{4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}[2-(3-hydroxybutyl)benzofuran-3-yl]methanone hydrochloride (516508-80-8)

Guidance literature:

With CYP₂J₂ supersomes; NADPH; magnesium chloride; at 37 ℃; for 1h; pH=7.4; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1124/dmd.111.043505

upstream raw materials:

amiodarone hydrochloride

Refernces