1-bromo-4-(4-methylsulfonylphenoxy)benzene

Base Information

• Chemical Name: 1-bromo-4-(4-methylsulfonylphenoxy)benzene
• CAS No.: 83642-28-8
• Molecular Formula: C13H11 Br O3 S
• Molecular Weight: 327.199
• Hs Code.: 2909309090
• Mol file: 83642-28-8.mol

Synonyms:1-Bromo-4-[4-(methylsulfonyl)phenoxy]benzene

Chemical Property of 1-bromo-4-(4-methylsulfonylphenoxy)benzene

Chemical Property:

• Vapor Pressure: 8.65E-08mmHg at 25°C
• Boiling Point: 447.8°C at 760 mmHg
• Flash Point: 224.6°C
• PSA: 51.75000
• Density: 1.5g/cm³
• LogP: 4.72570

Purity/Quality:

97% ^*data from raw suppliers

1-(4-BROMOPHENOXY)-4-METHANESULFONYLBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-bromo-4-(4-methylsulfonylphenoxy)benzene

There total 2 articles about 1-bromo-4-(4-methylsulfonylphenoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

4-bromo-phenol (106-41-2) + 1-iodo-4-(methylsulfonyl)benzene (64984-08-3) → 1-bromo-4-(4-(methylsulfonyl)phenoxy)benzene (83642-28-8)

Guidance literature:

With copper(l) iodide; In dimethyl sulfoxide; at 100 ℃; for 24h; Inert atmosphere;

Reference yield:

4-methanesulfonylphenylamine (5470-49-5) → 1-bromo-4-(4-(methylsulfonyl)phenoxy)benzene (83642-28-8)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride; sodium nitrite; potassium iodide / water / 1.5 h / 0 °C

2: copper(l) iodide / dimethyl sulfoxide / 24 h / 100 °C / Inert atmosphere

With hydrogenchloride; copper(l) iodide; potassium iodide; sodium nitrite; In water; dimethyl sulfoxide;

upstream raw materials:

4-methanesulfonylphenylamine

4-bromo-phenol

1-iodo-4-(methylsulfonyl)benzene

Refernces

• 1、 -. "DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE". . . Retrieved 2019/01/17.