64984-08-3

Basic information

• Product Name: 1-Iodo-4-(methylsulfonyl)benzene
• Synonyms: 1-Iodo-4-(methylsulfonyl)benzene
• CAS NO: 64984-08-3
• Molecular Formula: C₇H₇IO₂S
• Molecular Weight: 282.09875
• Mol File: 64984-08-3.mol
• Article Data: 19

Chemical Properties

• Melting Point: 116-118 °C
• Boiling Point: 365.7±34.0 °C(Predicted)
• Appearance: /
• Density: 1.840±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-Iodo-4-(methylsulfonyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Iodo-4-(methylsulfonyl)benzene(64984-08-3)
• EPA Substance Registry System: 1-Iodo-4-(methylsulfonyl)benzene(64984-08-3)

Safety Data

• Hazardous Substances Data: 64984-08-3(Hazardous Substances Data)

Usage

General Description

1-Iodo-4-(methylsulfonyl)benzene is a chemical compound with the molecular formula C7H7IO2S. It is an organoiodine compound that contains a benzene ring with a molecular structure consisting of a methylsulfonyl group and an iodine atom attached to it. 1-Iodo-4-(methylsulfonyl)benzene is used as a reagent in organic synthesis and medicinal chemistry, particularly in the production of pharmaceuticals and agrochemicals. It is also used in the manufacturing of dyes, imaging agents, and other specialty chemicals. 1-Iodo-4-(methylsulfonyl)benzene is known for its ability to undergo various chemical reactions, including substitution, elimination, and addition reactions, making it a versatile and important compound in the field of organic chemistry.

Upstream product

• 5470-49-5 4-methanesulfonylphenylamine 
• 104-96-1 4-methylsulfanylaniline 
• 4052-30-6 4-methylsulfonylbenzoic acid 
• 98-61-3 p-Iodobenzenesulfonyl chloride 
• 62696-04-2 TBHP 
• 2751-27-1 4-iodobenzenesulfonyl hydrazide 
• 149104-88-1 4-methanesulphonylphenylboronic acid 
• 35371-03-0 4-iodothioanisole 

Downstream Products

• 33592-56-2 1-[4-(methylsulfonyl)phenyl]-2-phenylacetylene 
• 64528-20-7 3-(4-Iodo-benzenesulfonyl)-2-oxo-propionic acid ethyl ester 
• 1598432-00-8 1-(methylsulfonyl)-4-(2,2,2-trifluoroethyl)benzene 
• 6462-34-6 4-(methylsulfonyl)-1,1′-biphenyl 
• 603143-27-7 (4,4,5,5-tetramethyl-2-[4-(methylsulfonyl)phenyl])-1,3,2-dioxaborolane 
• 83642-28-8 1-bromo-4-(4-(methylsulfonyl)phenoxy)benzene 
• 105135-96-4 3-(4-(methylsulfonyl)phenyl)prop-2-yn-1-ol 

Relevant articles and documents

Photoinduced Acetylation of Anilines under Aqueous and Catalyst-Free Conditions

A green and efficient visible-light induced functionalization of anilines under mild conditions has been reported. Utilizing nontoxic, cost-effective, and water-soluble diacetyl as photosensitizer and acetylating reagent, and water as the solvent, a variety of anilines were converted into the corresponding aryl ketones, iodides, and bromides. With advantages of environmentally friendly conditions, simple operation, broad substrate scope, and functional group tolerance, this reaction represents a valuable method in organic synthesis.

Electrochemical oxidations of thioethers: Modulation of oxidation potential using a hydrogen bonding network

A highly efficient chemo-selective electrochemical oxidation of thioethers to sulfoxides and sulfones was developed. The hydrogen bonding network generated from hexafluoro-2-propanol (HFIP) and acetic acid (AcOH) plays an important role in the modulation of oxidation potential. The hydrogen bonding network complexes strongly with the sulfoxide, making it less prone to further oxidation. Therefore, thioethers can be selectively electrochemically oxidized to sulfoxides and over-oxidization could be minimized. Moreover, this modulation of oxidization via hydrogen bonding was supported by density functional theory (DFT) calculations and cyclic voltammetry experiments.

Method for catalyzing deaminized boric acid esterification or halogenation of arylamine

The invention belongs to the technical field of organic synthesis and in particular discloses a method for catalyzing deaminized boric acid esterification or halogenation of arylamine. The method comprises the following steps: putting arylamine and a nitroso type compound into a mixed solvent, and performing a reaction at 0-5 DEG; and further adding a raw material capable of providing a functionalization group A and a catalysis amount of a reaction accelerator, and performing deamination functionalization reaction under light radiation at 10-50 DEG C, so as to obtain a product that an amino site of the arylamine is modified by the functionalization group A. Due to synergetic control on substrates, reaction solvents, material mixing modes, temperatures, reaction accelerators and addition amounts, boric acid esterification or halogenation of arylamine, particularly electron donating substituted arylamine which is hard to treat effectively in technical schemes of the industry, can be achieved.