1598432-00-8

Basic information

• Product Name: 1-(methylsulfonyl)-4-(2,2,2-trifluoroethyl)benzene
• Synonyms: 1-(methylsulfonyl)-4-(2,2,2-trifluoroethyl)benzene
• CAS NO: 1598432-00-8
• Molecular Weight: 238.23
• Mol File: 1598432-00-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(methylsulfonyl)-4-(2,2,2-trifluoroethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(methylsulfonyl)-4-(2,2,2-trifluoroethyl)benzene(1598432-00-8)
• EPA Substance Registry System: 1-(methylsulfonyl)-4-(2,2,2-trifluoroethyl)benzene(1598432-00-8)

Safety Data

• Hazardous Substances Data: 1598432-00-8(Hazardous Substances Data)

Upstream product

• 353-83-3 1,1,1-trifluoro-2-iodoethane 
• 64984-08-3 1-iodo-4-(methylsulfonyl)benzene 

Relevant articles and documents

Preparation method of trifluoroethyl compounds

The invention discloses a preparation method of trifluoroethyl compounds. The trifluoroethyl compounds are synthesized by directly using cheap and abundant industrial raw materials 2-chloro-1,1,1-trifluoroethane and halogenated substances as raw materials by stirring in a polar solvent under the action of a catalytic system using cheap and an easily available alkali metal nickel salt catalyst anda pyridine ligand for reacting under mild reaction conditions of 50-90 DEG C for 12-24 hours, and the efficient introduction of the trifluoroethyl groups to aromatic ring groups or heterocyclic aryl groups can be realized to prepare the trifluoroethyl compounds. The method has the advantages of mild reaction conditions, simple operation, low cost of raw materials and catalysts, good compatibilityof substrate functional groups, easy expansion of reaction scale, simple separation of products and suitability for industrial production.