threo-p-nitrobenzoate of methyl 4-hydroxy-5-methoxytetrahydrofuran-3-carboxylate

Base Information

• Chemical Name: threo-p-nitrobenzoate of methyl 4-hydroxy-5-methoxytetrahydrofuran-3-carboxylate
• CAS No.: 134734-19-3
• Molecular Formula: C₁₄H₁₅NO₈
• Molecular Weight: 325.275
• Mol file: 134734-19-3.mol

Synonyms:

Chemical Property of threo-p-nitrobenzoate of methyl 4-hydroxy-5-methoxytetrahydrofuran-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of threo-p-nitrobenzoate of methyl 4-hydroxy-5-methoxytetrahydrofuran-3-carboxylate

There total 4 articles about threo-p-nitrobenzoate of methyl 4-hydroxy-5-methoxytetrahydrofuran-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2,3-dihydro-3-furoate (53299-42-6,57371-05-8) → erythro-p-nitrobenzoate of methyl 4-hydroxy-5-methoxytetrahydrofuran-3-carboxylate (134734-19-3,134734-22-8)

Guidance literature:

Multi-step reaction with 2 steps

1: m-chloroperbenzoic acid / 1 h / 0 °C

2: pyridine / Ambient temperature

With pyridine; 3-chloro-benzenecarboperoxoic acid;

DOI:10.1002/jhet.5570280315

Reference yield:

methyl 2,3-dihydro-3-furoate (53299-42-6,57371-05-8) → threo-p-nitrobenzoate of methyl 4-hydroxy-5-methoxytetrahydrofuran-3-carboxylate (134734-19-3,134734-22-8)

Guidance literature:

Multi-step reaction with 2 steps

1: m-chloroperbenzoic acid / 1 h / 0 °C

2: pyridine / Ambient temperature

With pyridine; 3-chloro-benzenecarboperoxoic acid;

DOI:10.1002/jhet.5570280315

Reference yield:

4-nitro-benzoyl chloride (122-04-3) + methyl 4-hydroxy-5-methoxytetrahydrofuran-3-carboxylate → erythro-p-nitrobenzoate of methyl 4-hydroxy-5-methoxytetrahydrofuran-3-carboxylate (134734-19-3,134734-22-8) + threo-p-nitrobenzoate of methyl 4-hydroxy-5-methoxytetrahydrofuran-3-carboxylate (134734-19-3,134734-22-8)

Guidance literature:

With pyridine; Ambient temperature;

DOI:10.1002/jhet.5570280315

upstream raw materials:

4-nitro-benzoyl chloride

methyl 2,3-dihydro-3-furoate

Refernces