2-Propenoic acid, 3-(4-methylphenyl)-, (Z)-

Base Information

• Chemical Name: 2-Propenoic acid, 3-(4-methylphenyl)-, (Z)-
• CAS No.: 14290-88-1
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Mol file: 14290-88-1.mol

Synonyms:

Chemical Property of 2-Propenoic acid, 3-(4-methylphenyl)-, (Z)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propenoic acid, 3-(4-methylphenyl)-, (Z)-

There total 10 articles about 2-Propenoic acid, 3-(4-methylphenyl)-, (Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

ethyl (Z)-3-(4-methylphenyl)-2-propenoate (20511-20-0,24393-49-5,97585-04-1) → (2Z)-3-(4-methylphenyl)propenoic acid (14290-88-1,940-61-4)

Guidance literature:

With water; sodium hydroxide; In ethanol; at 20 ℃; for 4h;

DOI:10.1016/j.phytochem.2013.08.013

Reference yield: 58.0%

toluene (108-88-3,15644-74-3,16713-13-6) + Propiolic acid (471-25-0) → 3,3-bis(4-methylphenyl)propionic acid (95269-68-4) + 3-(2-methylphenyl)-3-(4-methylphenyl)propionic acid (1193386-10-5) + (2Z)-3-(2-methylphenyl)propenoic acid (41397-71-1) + (2Z)-3-(4-methylphenyl)propenoic acid (14290-88-1,940-61-4) + trans-p-methylcinnamic acid (1866-39-3,940-61-4)

Guidance literature:

With potassium tetrachloroplatinate; silver trifluoromethanesulfonate; trifluoroacetic acid; at 30 ℃; for 42h; optical yield given as %de;

DOI:10.1016/j.jorganchem.2009.07.008

Reference yield: 48.0%

toluene (108-88-3,15644-74-3,16713-13-6) + Propiolic acid (471-25-0) → 3,3-bis(4-methylphenyl)propionic acid (95269-68-4) + 3-(2-methylphenyl)-3-(4-methylphenyl)propionic acid (1193386-10-5) + (2Z)-3-(2-methylphenyl)propenoic acid (41397-71-1) + (2Z)-3-(4-methylphenyl)propenoic acid (14290-88-1,940-61-4)

Guidance literature:

With potassium tetrachloroplatinate; silver trifluoromethanesulfonate; trifluoroacetic acid; at 30 ℃; for 25h; optical yield given as %de;

DOI:10.1016/j.jorganchem.2009.07.008

upstream raw materials:

carbon monoxide

(Z)-1-[2-bromovinyl]-4-methylbenzene

trans-p-methylcinnamic acid

2,3-dibromo-3-p-tolyl-propionic acid

Downstream raw materials:

3-Chlor-6-methyl-benzo--thiophen-2-carbonsaeurechlorid

Refernces

• 1、 Nishikawa, Keisuke,Fukuda, Hiroshi,Abe, Masato,Nakanishi, Kazunari,Taniguchi, Tomoya,Nomura, Takashi,Yamaguchi, Chihiro,Hiradate, Syuntaro,Fujii, Yoshiharu,Okuda, Katsuhiro,Shindo, Mitsuru. "Substituent effects of cis-cinnamic acid analogues as plant growh inhibitors". . p. 132 - 147. Retrieved 2014/01/06.
• 2、 Oyamada, Juzo,Hashimoto, Takuya,Kitamura, Tsugio. "A high hydroarylation activity of K2PtCl4/AgOTf catalyst in the reaction of propiolic acid with unactivated and activated arenes". experimental part. p. 3626 - 3632. Retrieved 2010/01/18.