CIS-1,2-DICHLOROCYCLOHEXANE

Base Information

• Chemical Name: CIS-1,2-DICHLOROCYCLOHEXANE
• CAS No.: 10498-35-8
• Molecular Formula: C6H10Cl2
• Molecular Weight: 153.051
• Hs Code.: 2903890090
• Mol file: 10498-35-8.mol

Synonyms:Cyclohexane,1,2-dichloro-, cis- (8CI);cis-1,2-Dichlorocyclohexane;(1R,2S)-1,2-Dichlorocyclohexane;Cyclohexane, 1,2-dichloro-, (1R,2S)-;AC1L2559;CID66334;Cyclohexane, 1,2-dichloro-, cis-;

Chemical Property of CIS-1,2-DICHLOROCYCLOHEXANE

Chemical Property:

• Vapor Pressure: 0.333mmHg at 25°C
• Melting Point: -1.5°C
• Refractive Index: 1.472
• Boiling Point: 206.9 °C at 760 mmHg
• Flash Point: 66.1 °C
• PSA: 0.00000
• Density: 1.14 g/cm³
• LogP: 2.77520

Purity/Quality:

98%,99%, ^*data from raw suppliers

cis-1,2-Dichlorocyclohexane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: cis-1,2-Dichlorocyclohexane is used in preparation of organic halides from organotellurium(IV) halides by elimination reaction.

Technology Process of CIS-1,2-DICHLOROCYCLOHEXANE

There total 14 articles about CIS-1,2-DICHLOROCYCLOHEXANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-Chlorocyclohexyltellurium trichloride (27334-16-3,87099-41-0,87099-42-1) → cis-1,2-dichloro-cyclohexane (10498-35-8) + trans-1,2-dichlorocyclohexane (822-86-6)

Guidance literature:

With tert.-butylhydroperoxide; In 1,4-dioxane; for 0.5h; Heating;

DOI:10.1039/c39800001033

Reference yield: 80.0%

cyclohexene (110-83-8) → cis-1,2-dichloro-cyclohexane (10498-35-8)

Guidance literature:

With Phenylselenyl chloride; tetrabutyl-ammonium chloride; In N,N-dimethyl-formamide; at 20 ℃; Electrochemical reaction;

DOI:10.1002/chem.202103316

Reference yield: 55.0%

cyclohexane-1,2-epoxide (286-20-4) → cis-1,2-dichloro-cyclohexane (10498-35-8)

Guidance literature:

With sulfuryl dichloride; In dichloromethane; for 6h; Heating;

DOI:10.1016/S0040-4039(00)96074-X

upstream raw materials:

1-chlorocyclohexene

trans-2-chlorocyclohexanol

1,1-dichlrocyclohexane

2-Chlorocyclohexyltellurium trichloride

Downstream raw materials:

hydrogenchloride

1-chlorocyclohexene

cyclohexene

1,1-dimethylcyclohexane

Refernces

• 1、 Uemura et al.. "". . p. 1064. Retrieved 1971.
• 2、 Nugent,W.A.. "-". . p. 3427 - 3430. Retrieved 1978.
• 3、 Zeng, Xianghua,Gong, Chunhua,Zhang, Junyong,Xie, Jingli. "Organoselenium-catalyzed vicinal dichlorination of unsaturated phosphonates". . p. 7866 - 7871. Retrieved 2016.
• 4、 San Filippo,J. et al.. "-". . p. 1599 - 1600. Retrieved 1975.
• 5、 Stevens,Grummitt. "-". . p. 4876,4879. Retrieved 1952.
• 6、 Cresswell, Alexander J.,Eey, Stanley T.-C.,Denmark, Scott E.. "Catalytic, stereospecific syn-dichlorination of alkenes". . p. 146 - 152. Retrieved 2015.
• 7、 Parnes, Z. N.,Romanova, V. S.,Vol'pin, M. E.. "IONIC METHYLATION OF DICHLORO- AND DIBROMOALKANES". . p. 258 - 260. Retrieved 2007/10/02.