4-CARBOETHOXYBENZOPHENONE

Base Information

• Chemical Name: 4-CARBOETHOXYBENZOPHENONE
• CAS No.: 15165-27-2
• Molecular Formula: C16H14O3
• Molecular Weight: 254.285
• Hs Code.: 2918300090
• Mol file: 15165-27-2.mol

Synonyms:4-benzoyl-benzoic acid ethyl ester;ethyl 4-benzoyl-benzoate;Benzophenone,4'-(ethoxycarbonyl);4-carboethoxybenzophenone;4-ethoxycarbonylbenzophenone;ethyl p-benzoylbenzoate;3-benzoylbenzoic acid ethyl ester;

Chemical Property of 4-CARBOETHOXYBENZOPHENONE

Chemical Property:

• Vapor Pressure: 2.29E-06mmHg at 25°C
• Melting Point: 54-55 °C
• Boiling Point: 392.5oC at 760 mmHg
• Flash Point: 173.8oC
• PSA: 43.37000
• Density: 1.145g/cm3
• LogP: 3.09430

Purity/Quality:

98%min ^*data from raw suppliers

4-Carboethoxybenzophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CARBOETHOXYBENZOPHENONE

There total 30 articles about 4-CARBOETHOXYBENZOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

ethanol (64-17-5) + 4-carboxybenzophenone (611-95-0) → ethyl 4-benzoylbenzoate (15165-27-2)

Guidance literature:

With sulfuric acid; In cyclohexane; Reflux;

DOI:10.1080/14756366.2020.1748024

Reference yield: 95.0%

4-iodobenzoic acid ethyl ester (51934-41-9) + benzoyl chloride (98-88-4) → ethyl 4-benzoylbenzoate (15165-27-2)

Guidance literature:

4-iodobenzoic acid ethyl ester; With lithium di(2,2-dimethyl-2-phenylethyl)cuprate; In tetrahydrofuran; at -30 - 20 ℃;

benzoyl chloride; In tetrahydrofuran; at 20 ℃;

DOI:10.1002/1521-3773(20020902)41:17<3263::AID-ANIE3263>3.0.CO;2-8

Reference yield: 94.0%

3-iodobenzoic acid methyl ester (58313-23-8) + benzoyl chloride (98-88-4) → ethyl 4-benzoylbenzoate (15165-27-2)

Guidance literature:

3-iodobenzoic acid methyl ester; With pentamethylenebis(magnesium bromide); In tetrahydrofuran; at -78 - 20 ℃; for 1h;

benzoyl chloride; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1055/s-2003-43358

upstream raw materials:

ethanol

4-carboxybenzophenone

Ethyl 4-bromobenzoate

benzoyl chloride

Downstream raw materials:

1-benzyl-3-(4'-ethoxycarbonylphenyl)indazole

ethyl 4-[(8-phenethyl-8-azabicyclo[3.2.1]oct-3-ylidene)phenylmethyl]benzoate

ethyl 4-[(phenylhydrazono)(phenyl)methyl]benzoate

4-(hydroxymethyl)benzophenone

Refernces

• 1、 He, Min,Yu, Xiaoqiang,Wang, Yi,Li, Fei,Bao, Ming. "Self-Assembled 2,3-Dicyanopyrazino Phenanthrene Aggregates as a Visible-Light Photocatalyst". . p. 5016 - 5025. Retrieved 2021/04/12.
• 2、 Ali, Lamiaa M. A.,Baccon-Sollier, Paul Le,Cuq, Pierre,Lichon, Laure,Malki, Yohan,Masurier, Nicolas,Maye, Morgane,Vincent, Laure-Ana?s. "Imidazopyridine-fused [1,3]diazepinones: modulations of positions 2 to 4 and their impacts on the anti-melanoma activity". . p. 935 - 949. Retrieved 2020/04/17.