4-Pentyn-1-amine

Base Information

• Chemical Name: 4-Pentyn-1-amine
• CAS No.: 15252-44-5
• Molecular Formula: C5H9N
• Molecular Weight: 83.1332
• Mol file: 15252-44-5.mol

Synonyms:pent-4-yn-1-amine;1-Amino-4-pentyne 4-Pentynylamine 5-Amino-1-pentyne;

Chemical Property of 4-Pentyn-1-amine

Chemical Property:

• Boiling Point: 118.0±23.0 °C(Predicted)
• PKA: 9.76±0.10(Predicted)
• Flash Point: 10 - 15°C
• PSA: 26.02000
• Density: 0.859g/mLat 20℃
• LogP: 1.05880
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s): 2232239
• Hazard Codes: F,C
• Statements: 11-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-Pentyn-1-amine

There total 10 articles about 4-Pentyn-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N-(pent-4-ynyl)phthalimide (6097-07-0) → 1-amino-pent-4-yne (15252-44-5)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 1h;

Reference yield: 84.0%

pent-4-yn-1-yl methanesulfonate (68275-03-6) → 1-amino-pent-4-yne (15252-44-5)

Guidance literature:

With ammonium hydroxide; at 80 ℃; Sealed tube;

Reference yield: 60.0%

pent-4-ynyl-1-azide (199276-58-9) → 1-amino-pent-4-yne (15252-44-5)

Guidance literature:

With triphenylphosphine; In diethyl ether; at 0 ℃; for 2.5h;

DOI:10.1002/ejoc.201900701

upstream raw materials:

sodium acetylide

3-bromopropylamine hydrochloride

acetylene

N-(pent-4-ynyl)phthalimide

Downstream raw materials:

1,1-Diphenyl-1-hydroxy-6-amino-hexin-⁽²⁾

1-Amino-8,8-diphenyl-8-hydroxy-octadiin-(4,6)

4-pentenyl-1-amine

3-methylidene-2-oxo-piperidine

Refernces

• 1、 Huang, Boxuan,Li, Weijia,Mu, Yu,Shao, Liang,Su, Yangqing,Sun, Mengsi,Xu, Huan,Yang, Fan,Yu, Fei,Zhang, Jihong,Zhang, Yuan. "Design and Synthesis of Oleanolic Acid Trimers to Enhance Inhibition of Influenza Virus Entry". . p. 1759 - 1765. Retrieved 2021/11/18.
• 2、 Zelenay, Benjamin,Munton, Peter,Tian, Xiaojie,Díez-González, Silvia. "A Commercially Available and User-Friendly Catalyst for Hydroamination Reactions under Technical Conditions". . p. 4725 - 4730. Retrieved 2019/08/01.