1α-Bromo-2β-methoxycyclohexane

Base Information

• Chemical Name: 1α-Bromo-2β-methoxycyclohexane
• CAS No.: 24618-31-3
• Molecular Formula: C7H13 Br O
• Molecular Weight: 193.084
• Mol file: 24618-31-3.mol

Synonyms:Ether,2-bromocyclohexyl methyl (7CI,8CI); 1-Bromo-2-methoxycyclohexane; NSC 155566

Chemical Property of 1α-Bromo-2β-methoxycyclohexane

Chemical Property:

• Vapor Pressure: 0.517mmHg at 25°C
• Refractive Index: 1.4871 (estimate)
• Boiling Point: 198°C at 760 mmHg
• Flash Point: 77.7°C
• PSA: 9.23000
• Density: 1.31g/cm³
• LogP: 2.33890

Purity/Quality:

99%min ^*data from raw suppliers

1-bromo-2-methoxycyclohexane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1α-Bromo-2β-methoxycyclohexane

There total 23 articles about 1α-Bromo-2β-methoxycyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + cyclohexene (110-83-8) → bromo-1 methoxy-2 cyclohexane (24618-31-3)

Guidance literature:

With N-Bromosuccinimide;

DOI:10.1016/S0040-4039(00)99928-3

Reference yield: 52.0%

cyclohexene (110-83-8) → 1,2-dibromocyclohexane (5401-62-7) + bromo-1 methoxy-2 cyclohexane (24618-31-3)

Guidance literature:

With bromine; sodium bromide; In methanol; at 25 ℃;

Reference yield: 48.0%

methanol (67-56-1) + cyclohexene (110-83-8) → bromo-1 methoxy-2 cyclohexane (24618-31-3) + N-((1S,2R)-2-Bromo-cyclohexyl)-2-chloro-acetamide (35077-28-2,35077-29-3) + N-(trans-2-bromocyclohexyl)chloroacetamide (35077-28-2,35077-29-3)

Guidance literature:

With α-chloro-N-bromoacetamide; In dichloromethane; at -70 ℃; for 63h; Yields of byproduct given; Irradiation;

upstream raw materials:

methanol

peracetic acid

cyclohexene

5,5-dibromobarbituric acid

Downstream raw materials:

tributyltin bromide

2-(2-cyclohepten-1-yl)phenol

Cyclohex-2-enol

3-methoxycyclohexene

Refernces

• 1、 Boerwinkle,Hassner. "". . p. 3921. Retrieved 1968.
• 2、 Nikishin, Gennady I.,Elinson, Michail N.,Makhova, Irina V.. "ELAECTROCHEMICAL OXIDATION OF CONJUGATED ARYLOLEFINS TO α-BROMOKETALS". . p. 1603 - 1604. Retrieved 2007/10/02.