2-chloro-5-iodoaniline

Base Information

• Chemical Name: 2-chloro-5-iodoaniline
• CAS No.: 16604-98-1
• Molecular Formula: C6H5ClIN
• Molecular Weight: 253.47
• Hs Code.: 2921420090
• Mol file: 16604-98-1.mol

Synonyms:2-Chlor-5-jod-anilin;2-CHLORO-5-IODOPHENYLAMINE;2-Chlor-5-iod-anilin;2-chloro-5-iodo-aniline;

Chemical Property of 2-chloro-5-iodoaniline

Chemical Property:

• PSA: 26.02000
• LogP: 3.10800

Purity/Quality:

98%min ^*data from raw suppliers

2-CHLORO-5-IODOANILINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-chloro-5-iodoaniline

There total 3 articles about 2-chloro-5-iodoaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chloro-4-iodo-2-nitrobenzene (41252-95-3) → 2-chloro-5-iodoaniline (16604-98-1)

Guidance literature:

With ethanol; titanium chloride;

Reference yield:

4-Chloro-3-nitroaniline (635-22-3) → 2-chloro-5-iodoaniline (16604-98-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous H₂SO₄ / Diazotization_.Behandlung der Diazoniumsalz-Loesung mit Ki, zuletzt auf dem Dampfbad

2: aqueous titanium (II)-chloride; ethanol

With ethanol; sulfuric acid; titanium chloride;

Reference yield:

3,4-dinitroaniline (610-41-3) → 2-chloro-5-iodoaniline (16604-98-1)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; sulfuric acid; sodium nitrite / anschliessendes Behandeln mit Kaliumjodid-Loesung

2: aqueous HCl; tin

With hydrogenchloride; tin; sulfuric acid; acetic acid; sodium nitrite;

upstream raw materials:

1-chloro-4-iodo-2-nitrobenzene

3,4-dinitroaniline

4-Chloro-3-nitroaniline

Downstream raw materials:

tert-butyl 3-{3-[bis(4-methoxybenzyl)amino]-4-chlorophenyl}-3-(1-methylcyclopropyl)propanoate

{3-[bis(4-methoxybenzyl)amino]-4-chlorophenyl}(1-methylcyclopropyl)methanone

tert-butyl 3-(3-amino-4-chlorophenyl)-3-(1-methylcyclopropyl)propanoate

2-chloro-5-iodo-N,N-bis(4-methoxybenzyl)aniline

Refernces

• 1、 -. "PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS". Page/Page column 55-56. . Retrieved 2010/02/15.