1-(3-Butyloxiranyl)ethanone

Base Information

• Chemical Name: 1-(3-Butyloxiranyl)ethanone
• CAS No.: 17257-80-6
• Molecular Formula: C8H14O2
• Molecular Weight: 142.198
• Hs Code.: 2914190090
• Mol file: 17257-80-6.mol

Synonyms:3,4-epoxyoctan-2-one;2-Octanone,3,4-epoxy;3,4-Epoxy-octan-2-on;Z-3,4-epoxy-2-octanone;

Chemical Property of 1-(3-Butyloxiranyl)ethanone

Chemical Property:

• PSA: 29.60000
• LogP: 1.53300

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3-Butyloxiranyl)ethanone

There total 9 articles about 1-(3-Butyloxiranyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

threo-3,4-epoxy-2-octanol (93399-87-2,109837-35-6,109837-36-7,111321-51-8,111321-52-9,131233-05-1) → Z-3,4-epoxy-2-octanone (17257-80-6,420849-79-2)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; -60 deg C, 2 min, then -60 deg C, 15 min;

Reference yield: 68.0%

(3E)-oct-3-en-2-one (18402-82-9) → Z-3,4-epoxy-2-octanone (17257-80-6,420849-79-2)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 120h;

DOI:10.1016/j.tetlet.2006.06.009

Reference yield: 40.0%

oct-2-yne (2809-67-8) → Z-3,4-epoxy-2-octanone (17257-80-6,420849-79-2) + oct-1-en-3-one (4312-99-6) + (3E)-oct-3-en-2-one (18402-82-9) + hexanoic acid (142-62-1)

Guidance literature:

With dihydrogen peroxide; tris(cetylpyridinium) 12-tungstophosphate; In chloroform; for 24h; Further byproducts given; Heating;

DOI:10.1021/jo00308a002

upstream raw materials:

oct-2-yne

threo-3,4-epoxy-2-octanol

3-octen-2-one

(3E)-oct-3-en-2-one

Downstream raw materials:

3-octen-2-one

(Z)-oct-2-en-4-ol

(E)-oct-2-en-4-ol

(2S,3R)-1-(3-butyl-oxiranyl)-ethanone

Refernces

• 1、 Gravil, Sébastien,Veschambre, Henri,Chênevert, Robert,Bolte, Jean. "First lipase catalysed resolution of epoxy enol esters". . p. 6153 - 6157. Retrieved 2007/10/03.
• 2、 Hunter,Turner,Rimmer. "Aerobic epoxidation of alkenes catalysed by cobalt(II) 1,1,1,5,5,5-hexafluoroacetylacetonate or cobalt(II) benzoylacetonate". . p. 4461 - 4466. Retrieved 2007/10/03.