PentaniMidaMide Hydrochloride

Base Information

• Chemical Name: PentaniMidaMide Hydrochloride
• CAS No.: 18257-46-0
• Molecular Formula: C5H12N2·ClH
• Molecular Weight: 136.625
• Hs Code.: 2925290090
• Mol file: 18257-46-0.mol

Synonyms:Pentanimidamide, hydrochloride (1:1);Butylamidine hydrochloride;Valeramidine hydrochloride;

Chemical Property of PentaniMidaMide Hydrochloride

Chemical Property:

• Boiling Point: 141.9 °C at 760 mmHg
• Flash Point: 39.6 °C
• PSA: 49.87000
• LogP: 2.71460

Purity/Quality:

98%,99%, ^*data from raw suppliers

Pentanimidamidehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PentaniMidaMide Hydrochloride

There total 4 articles about PentaniMidaMide Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

pentanonitrile (110-59-8) → pentanamidine hydrochloride (18257-46-0)

Guidance literature:

pentanonitrile; With hydrogenchloride; In methanol; at 0 - 10 ℃; for 9h;

With ammonia; In methanol; at 0 - 20 ℃; pH=8.5;

Reference yield:

→ pentanamidine hydrochloride (18257-46-0)

Guidance literature:

With ethanol; ammonia;

DOI:10.1007/BF02864543

Reference yield:

methanol (67-56-1) + methyl pentanimidate hydrochloride (39739-46-3) → pentanamidine hydrochloride (18257-46-0)

Guidance literature:

In ammonia;

upstream raw materials:

methanol

methyl pentanimidate hydrochloride

ethyl valerimidate hydrochloride

pentanonitrile

Downstream raw materials:

2-butyl-4-methyl-1,6-dihydro-6-pyrimidone

6-benzyl-2-butyl-3H-pyrimidin-4-one

2-butyl-6-phenethyl-3H-pyrimidin-4-one

4-Hydroxy-6-methyl-2-butyl-pyrimidin

Refernces

• 1、 Choung, Wonken,Jung, Hui Jin,Nam, Eun Hye,Yang, Deokmo,Yoo, Byoungwook,Choi, Hyukjoon,Lee, Bo Ram,Park, Min,Jang, Su Min,Lim, Jae Soo,Kim, Kyung-Hee,Chin, Jungwook,Jung, Kyungjin,Lee, Geumwoo,Kim, Seong Heon. "Discovery of the bifunctional modulator of angiotensin II type 1 receptor (AT1R) and PPARγ derived from the AT1R antagonist, Fimasartan". . p. 3155 - 3160. Retrieved 2018/09/11.
• 2、 Kim, Tae Woo,Yoo, Byoung Wook,Lee, Joon Kwang,Kim, Ji Han,Lee, Kyung-Tae,Chi, Yong Ha,Lee, Jae Yeol. "Synthesis and antihypertensive activity of pyrimidin-4(3H)-one derivatives as losartan analogue for new angiotensin II receptor type 1 (AT1) antagonists". scheme or table. p. 1649 - 1654. Retrieved 2012/04/04.