Tipiracil

Base Information Edit

Chemical Name:Tipiracil
CAS No.:183204-74-2
Molecular Formula:C9H11ClN4O2
Molecular Weight:242.66200
Hs Code.:
UNII:NGO10K751P
DSSTox Substance ID:DTXSID601025833
Nikkaji Number:J1.090.874D
Wikipedia:Tipiracil
Wikidata:Q21098889
NCI Thesaurus Code:C152646
RXCUI:1670304
Pharos Ligand ID:JRPJ7XXGDTSX
Metabolomics Workbench ID:152347
ChEMBL ID:CHEMBL235668
Mol file:183204-74-2.mol

Synonyms:5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione;tipiracil

Suppliers and Price of Tipiracil

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Tipiracil 95+%
100mg
$ 139.00

Crysdot
Tipiracil 95+%
50mg
$ 104.00

Crysdot
Tipiracil 95+%
10mg
$ 52.00

ChemScene
Tipiracil
100mg
$ 240.00

ChemScene
Tipiracil
50mg
$ 180.00

ChemScene
Tipiracil
10mg
$ 90.00

ChemScene
Tipiracil
5mg
$ 60.00

Total 13 raw suppliers

Chemical Property of Tipiracil Edit

Chemical Property:

PKA:7.06±0.10(Predicted)
PSA：93.33000
Density:1.71±0.1 g/cm3(Predicted)
LogP:1.15190
XLogP3:-0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:242.0570533
Heavy Atom Count:16
Complexity:404

Purity/Quality:

98% min ^*data from raw suppliers

Tipiracil 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=N)N(C1)CC2=C(C(=O)NC(=O)N2)Cl
Recent ClinicalTrials:A Study to Evaluate the Safety and Efficacy of Selinexor With or Without Pembrolizumab Versus Standard of Care in Previously Treated Metastatic Colorectal Cancer With RAS Mutations
Recent EU Clinical Trials:A randomized, phase II study comparing the sequences of regorafenib and trifluridine/tipiracil, after failure of standard therapies in patients with metastatic colorectal cancer
Recent NIPH Clinical Trials:A phase I/II study for the safety and efficacy of Panitumumab in combination with TAS-102 for patients with colorectal cancer (APOLLON)

Technology Process of Tipiracil

There total 12 articles about Tipiracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.6%