L-Asparagine, L-cysteinyl-L-threonyl-L-seryl-L-isoleucyl-L-cysteinyl-L-seryl-L-leucyl-L-tyros yl-L-glutaminyl-L-leucyl-L-a-glutamyl-L-asparaginyl-L-tyrosyl-L-cysteinyl-

Base Information

• Chemical Name: L-Asparagine, L-cysteinyl-L-threonyl-L-seryl-L-isoleucyl-L-cysteinyl-L-seryl-L-leucyl-L-tyros yl-L-glutaminyl-L-leucyl-L-a-glutamyl-L-asparaginyl-L-tyrosyl-L-cysteinyl-
• CAS No.: 187170-61-2
• Molecular Formula: C₇₃H₁₁₂N₁₈O₂₆S₃
• Molecular Weight: 1754
• Mol file: 187170-61-2.mol

Synonyms:

Chemical Property of L-Asparagine, L-cysteinyl-L-threonyl-L-seryl-L-isoleucyl-L-cysteinyl-L-seryl-L-leucyl-L-tyros yl-L-glutaminyl-L-leucyl-L-a-glutamyl-L-asparaginyl-L-tyrosyl-L-cysteinyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-Asparagine, L-cysteinyl-L-threonyl-L-seryl-L-isoleucyl-L-cysteinyl-L-seryl-L-leucyl-L-tyros yl-L-glutaminyl-L-leucyl-L-a-glutamyl-L-asparaginyl-L-tyrosyl-L-cysteinyl-

There total 1 articles about L-Asparagine, L-cysteinyl-L-threonyl-L-seryl-L-isoleucyl-L-cysteinyl-L-seryl-L-leucyl-L-tyros yl-L-glutaminyl-L-leucyl-L-a-glutamyl-L-asparaginyl-L-tyrosyl-L-cysteinyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(tert-butyloxycarbonyl)-L-isoleucine (13139-16-7) + N-tert-butoxycarbonyl-L-leucine (13139-15-6,53296-34-7) + C16H29NO6 + C10H17N2O5Pol + Boc-Gln-OH (13726-85-7) + N-Boc-O-benzyl-L-threonine (15260-10-3) + BOC-O-benzyl-L-serine (23680-31-1) + Boc-cysteine(4-Me-Bn) (61925-77-7) + (S)-3-[4-(2-Bromo-benzyloxycarbonyloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid (47689-67-8) + (S)-2-tert-Butoxycarbonylamino-N-(9H-xanthen-9-yl)-succinamic acid (65420-40-8) → L-proinsulin(Cys72-Asn86) (187170-61-2)

Guidance literature:

C₁₀H₁₇N₂O₅Pol; (S)-2-tert-Butoxycarbonylamino-N-(9H-xanthen-9-yl)-succinamic acid; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; solid phase reaction;

With trifluoroacetic acid; solid phase reaction;

N-(tert-butyloxycarbonyl)-L-isoleucine; N-tert-butoxycarbonyl-L-leucine; C₁₆H₂₉NO₆; Boc-Gln-OH; N-Boc-O-benzyl-L-threonine; BOC-O-benzyl-L-serine; Boc-cysteine(4-Me-Bn); (S)-3-[4-(2-Bromo-benzyloxycarbonyloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid; Further stages;

DOI:10.1039/c0cc03141k

upstream raw materials:

N-(tert-butyloxycarbonyl)-L-isoleucine

N-tert-butoxycarbonyl-L-leucine

Boc-Gln-OH

N-Boc-O-benzyl-L-threonine

Refernces