2,5-Dibromo-4-methylbenzoic acid

Base Information

• Chemical Name: 2,5-Dibromo-4-methylbenzoic acid
• CAS No.: 20871-01-6
• Molecular Formula: C8H6Br2O2
• Molecular Weight: 293.942
• Hs Code.: 2916399090
• Mol file: 20871-01-6.mol

Synonyms:3,6-dibromo-4-toluic acid;2,5-Dibrom-4-methyl-benzoesaeure;2.5-Dibrom-p-toluylsaeure;2,5-dibromo-4-methyl-benzoic acid;

Chemical Property of 2,5-Dibromo-4-methylbenzoic acid

Chemical Property:

• PSA: 37.30000
• LogP: 3.21820

Purity/Quality:

95% ^*data from raw suppliers

2,5-Dibromo-4-methylbenzoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-Dibromo-4-methylbenzoic acid

There total 6 articles about 2,5-Dibromo-4-methylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2,5-dibromo-p-xylene (1074-24-4) → 2,5-dibromo-4-methylbenzoic acid (20871-01-6)

Guidance literature:

With water; nitric acid; at 100 ℃; for 168h;

DOI:10.1002/(SICI)1521-3773(19990816)38:16<2370::AID-ANIE2370>3.0.CO;2-T

Reference yield:

→ 2,5-dibromo-4-methylbenzoic acid (20871-01-6)

Guidance literature:

With nitric acid;

Reference yield:

para-xylene (106-42-3) → 2,5-dibromo-4-methylbenzoic acid (20871-01-6)

Guidance literature:

Multi-step reaction with 2 steps

1: iodine; bromine / 10 - 15 °C

2: aqueous nitric acid

With bromine; iodine; nitric acid;

upstream raw materials:

2,5-dibromo-p-xylene

nitric acid

para-xylene

2-bromo-1-isopropyl-4-methyl-benzene

Downstream raw materials:

2,5-dibromo-4-methylbenzoic acid methyl ester

2,5-dibromoterephtalic acid

2,5-dibromo-4-methylbenzohydrazide

N'-(2,5-dibromo-4-methylbenzoyl)thiophene-2-carbohydrazide

Refernces

• 1、 -. "PREPARING METHOD OF SYNTHESIZING INDACENO DITHIENOTHIOPHENE COMPOUND". Paragraph 0097-0100. . Retrieved 2019/12/25.
• 2、 Sung, Hsiao-Hsien,Lin, Hong-Cheu. "Novel alternating fluorene-based conjugated polymers containing oxadiazole pendants with various terminal groups". . p. 7945 - 7954. Retrieved 2007/10/03.