Triethylene glycol monophenyl ether

Base Information

• Chemical Name: Triethylene glycol monophenyl ether
• CAS No.: 7204-16-2
• Molecular Formula: C12H18 O4
• Molecular Weight: 226.273
• DSSTox Substance ID: DTXSID70222353
• Nikkaji Number: J104.660H
• Wikidata: Q83100558
• Mol file: 7204-16-2.mol

Synonyms:TRIETHYLENE GLYCOL MONOPHENYL ETHER;7204-16-2;2-[2-(2-Phenoxyethoxy)ethoxy]ethanol;Ph-PEG3;2-(2-(2-Phenoxyethoxy)ethoxy)ethan-1-ol;2-[2-(2-phenoxyethoxy)ethoxy]ethan-1-ol;Ethanol, 2-[2-(2-phenoxyethoxy)ethoxy]-;SCHEMBL408349;Triethylene glycol phenyl ether;DTXSID70222353;IDHKBOHEOJFNNS-UHFFFAOYSA-N;AMY30230;AKOS024355546;HY-W096158;ETHANOL,2-[2-(2-PHENOXYETHOXY;2-[2-(2-Phenoxyethoxy)ethoxy]ethanol #;AS-76935;CS-0147811;D93865;A1-05656

Chemical Property of Triethylene glycol monophenyl ether

Chemical Property:

• Vapor Pressure: 1.47E-05mmHg at 25°C
• Boiling Point: 351.9°C at 760 mmHg
• Flash Point: 166.6°C
• PSA: 47.92000
• Density: 1.097g/cm³
• LogP: 1.09090
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 226.12050905
• Heavy Atom Count: 16
• Complexity: 146

Purity/Quality:

99% ^*data from raw suppliers

2-[2-(2-Phenoxyethoxy)ethoxy]ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OCCOCCOCCO

Technology Process of Triethylene glycol monophenyl ether

There total 10 articles about Triethylene glycol monophenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-[2-(chloroethoxy)ethoxy]ethanol (5197-62-6) + phenol (108-95-2,27073-41-2) → 2-(2-(2-phenoxyethoxy)ethoxy)ethan-1-ol (7204-16-2,9004-78-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 18h; Inert atmosphere;

DOI:10.1021/acs.orglett.0c00830

Reference yield: 71.0%

triethylene glycol di-(p-toluenesulfonate) (19249-03-7) + phenol (108-95-2,27073-41-2) → 2-(2-(2-phenoxyethoxy)ethoxy)ethan-1-ol (7204-16-2,9004-78-8)

Guidance literature:

With potassium carbonate; In benzene; for 73h; Heating;

DOI:10.1021/jo00303a024

Reference yield: 67.0%

1-bromo-6-phenyl-3,6-dioxahexane (123824-56-6) + ethylene glycol (107-21-1) → 2-(2-(2-phenoxyethoxy)ethoxy)ethan-1-ol (7204-16-2,9004-78-8)

Guidance literature:

With potassium hydroxide; In water; 1.) 115 deg C, 1h; 2.) 120 deg C, 1h;

DOI:10.1016/S0040-4020(01)85934-2

upstream raw materials:

oxirane

phenol

sodium phenoxide

1-bromo-6-phenyl-3,6-dioxahexane

Downstream raw materials:

1-bromo-9-phenyl-3,6,9-trioxanonane

2-(2-(2-(4-bromophenoxy)ethoxy)ethoxy)ethan-1-ol

1-(2',4'-dinitrophenoxy)-8-phenoxy-3,6-dioxaoctane

1-(4'-nitrophenoxy)-8-phenoxy-3,6-dioxaoctane

Refernces

• 1、 Deng, Yan,Dong, Shengyi,Lai, Jinlei,Li, Xing,Zhao, Gai. "Tough, Long-Term, Water-Resistant, and Underwater Adhesion of Low-Molecular-Weight Supramolecular Adhesives". supporting information. p. 5371 - 5379. Retrieved 2020/04/09.
• 2、 Mertens, Ingrid J. A.,Wegh, Rene,Jenneskens, Leonardus W.,Vlietstra, Edward J.,Van Der Kerk-van Hoof, Anca,Zwikker, Jan W.,Cleij, Thomas J.,Smeets, Wilberth J. J.,Veldman, Nora,Spek, Anthony L.. "Formation of huge cyclic oligomers in the condensation polymerization of bis(9-hydroxy-1,4,7-trioxanonyl) substituted naphthalene and benzenes with both aromatic and aliphatic bis-acid chlorides". . p. 725 - 736. Retrieved 2007/10/03.