3-Phenyl-1,2,4-trioxolane

Base Information

• Chemical Name: 3-Phenyl-1,2,4-trioxolane
• CAS No.: 23253-30-7
• Molecular Formula: C8H8O3
• Molecular Weight: 152.15
• Hs Code.: 2914399090
• Mol file: 23253-30-7.mol

Synonyms:1,2,4-Trioxolane,3-phenyl;Benzene,ethenyl-,ozonide;styrene ozonide;Styrolozonid;

Chemical Property of 3-Phenyl-1,2,4-trioxolane

Chemical Property:

• PSA: 27.69000
• LogP: 1.62110

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Phenyl-1,2,4-trioxolane

There total 9 articles about 3-Phenyl-1,2,4-trioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → 3-Phenyl-1,2,4-trioxolane (23253-30-7) + benzaldehyde (100-52-7)

Guidance literature:

With ozone; triethylamine; In dichloromethane; water; at 0 ℃;

DOI:10.1016/j.tet.2006.08.092

Reference yield: 77.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → 3-Phenyl-1,2,4-trioxolane (23253-30-7)

Guidance literature:

With ozone;

DOI:10.1016/S0040-4039(99)01399-4

Reference yield: 8.5%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → formic acid (64-18-6) + 3-Phenyl-1,2,4-trioxolane (23253-30-7) + benzaldehyde (100-52-7) + benzoic acid (65-85-0,8013-63-6)

Guidance literature:

With ozone; at 20 ℃; for 0.25h; Further Variations:; Solvents; Product distribution;

upstream raw materials:

styrene

Methyl formate

acetic acid methyl ester

Styrolozonid

Downstream raw materials:

benzaldehyde

benzoic acid

1-Phenyl-3-buten-1-ol

3-Phenyl-1,2,4-trioxaspiro[5.4]decane

Refernces

• 1、 Kendall, Alexander J.,Barry, Justin T.,Seidenkranz, Daniel T.,Ryerson, Ajay,Hiatt, Colin,Salazar, Chase A.,Bryant, Dillon J.,Tyler, David R.. "Highly efficient biphasic ozonolysis of alkenes using a high-throughput film-shear flow reactor". supporting information. p. 1342 - 1345. Retrieved 2018/03/27.
• 2、 Dussault, Patrick H.,Lee, Hyung-Jae,Liu, Xuejun. "Selectivity in Lewis acid-mediated fragmentations of peroxides and ozonides: Application to the synthesis of alkenes, homoallyl ethers, and 1,2-dioxolanes". . p. 3006 - 3013. Retrieved 2007/10/03.