ethyl 7-chloroheptanoate

Base Information

• Chemical Name: ethyl 7-chloroheptanoate
• CAS No.: 26040-65-3
• Molecular Formula: C9H17ClO2
• Molecular Weight: 192.686
• Mol file: 26040-65-3.mol

Synonyms:7-chloro-heptanoic acid ethyl ester;Heptanoic acid,7-chloro-,ethyl ester;7-Chlor-heptansaeure-aethylester;7-Chlor-heptansaeureethylester;ethyl-7-chlorooenanthate;7-chloroenanthic acid ethyl ester;

Chemical Property of ethyl 7-chloroheptanoate

Chemical Property:

• Boiling Point: 122-123 °C(Press: 11 Torr)
• PSA: 26.30000
• Density: 1.0110 g/cm3
• LogP: 2.73880

Purity/Quality:

98.0%min ^*data from raw suppliers

Ethyl7-chloroheptanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 7-chloroheptanoate

There total 2 articles about ethyl 7-chloroheptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

Ethyl 4-bromobutyrate (2969-81-5) + C15H14ClO4Si(1-)*K(1+)*C12H24O6 → ethyl 7-chloroheptanoate (26040-65-3) + diethyl suberate (2050-23-9)

Guidance literature:

With [2,2]bipyridinyl; bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; Ir(dF(CF₃)ppy)2(bpy)PF₆; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Schlenk technique; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1002/ejoc.201601571

Reference yield:

ethanol (64-17-5) + 7-chloroheptanoic acid (821-57-8) → ethyl 7-chloroheptanoate (26040-65-3)

Guidance literature:

With sodium chloride;

Reference yield: 53.0%

ethyl 7-chloroheptanoate (26040-65-3) + C17H21BN2O2 + dimethylphenylvinylsilane (1125-26-4) → ethyl 8-(dimethyl(phenyl)silyl)-9-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)nonanoate

Guidance literature:

With 1,1'-bis-(diphenylphosphino)ferrocene; potassium tert-butylate; copper(l) chloride; In tetrahydrofuran; 1,4-dioxane; at 50 ℃; for 4h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.6b03820

upstream raw materials:

ethanol

7-chloroheptanoic acid

Ethyl 4-bromobutyrate

Downstream raw materials:

ethyl 6-heptenoate

N⁹-(ω-hydroxycarbonyl-n-hexyl)adenine

ethyl-7-(1,4,5-triphenylimidazol-2-yloxy)-oenanthate

7-[3-(3-Chlorophenyl)-2-oxo-benzimidazolin-1-yl]-enanthic ethyl ester

Refernces