isonicotinic acid [2-oxo-2-(5-phenyl-isoxazol-3-yl)-ethylidene]-hydrazide

Base Information

• Chemical Name: isonicotinic acid [2-oxo-2-(5-phenyl-isoxazol-3-yl)-ethylidene]-hydrazide
• CAS No.: 13788-08-4
• Molecular Formula: C₁₇H₁₂N₄O₃
• Molecular Weight: 320.307
• Mol file: 13788-08-4.mol

Synonyms:

Chemical Property of isonicotinic acid [2-oxo-2-(5-phenyl-isoxazol-3-yl)-ethylidene]-hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of isonicotinic acid [2-oxo-2-(5-phenyl-isoxazol-3-yl)-ethylidene]-hydrazide

There total 2 articles about isonicotinic acid [2-oxo-2-(5-phenyl-isoxazol-3-yl)-ethylidene]-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-acetyl-5-phenyl-isoxazole (7063-98-1) → isonicotinic acid [2-oxo-2-(5-phenyl-isoxazol-3-yl)-ethylidene]-hydrazide (13788-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1: SeO₂

With selenium(IV) oxide;

Reference yield:

oxo-(5-phenyl-isoxazol-3-yl)-acetaldehyde hydrate (13788-04-0) + isoniazid (54-85-3,7640-37-1) → isonicotinic acid [2-oxo-2-(5-phenyl-isoxazol-3-yl)-ethylidene]-hydrazide (13788-08-4)

Guidance literature:

upstream raw materials:

oxo-(5-phenyl-isoxazol-3-yl)-acetaldehyde hydrate

isoniazid

3-acetyl-5-phenyl-isoxazole

Refernces