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Name	Sodium butazolidine	EINECS	204-935-7
CAS No.	129-18-0	Density	1.063g/mLat 25°C(lit.)
PSA	49.99000	LogP	4.11460
Solubility	N/A	Melting Point	N/A
Formula	C₁₉H₂₀N₂NaO₂	Boiling Point	113°C27mm Hg(lit.)
Molecular Weight	331.40	Flash Point	95 °C
Transport Information	N/A	Appearance	gray powder complex
Safety		Risk Codes	R36/37/38
Molecular Structure		Hazard Symbols	C
Synonyms	3,5-Pyrazolidinedione,4-butyl-1,2-diphenyl-, ion(1-), sodium (8CI,9CI);3,5-Pyrazolidinedione,4-butyl-1,2-diphenyl-, sodium deriv. (6CI,7CI);Butazolidine sodium;Diphenyldioxobutylpyrazolidine;GP 26872;Phenylbutazone sodium;Phenylbutazone, sodium salt;Sodium phenylbutazone;

Sodium butazolidine Chemical Properties

Product Name: Sodium butazolidine
CAS Registry Number: 129-18-0
Molecular Formula: C₁₉H₂₀N₂NaO₂
Molar mass: 331.3635 g/mol
EINECS: 204-935-7
Structure of Sodium butazolidine (CAS NO.129-18-0):

Systematic Name: Sodium 4-butyl-1,2-diphenyl-pyrazolidine-3,5-dione
SMILES: [Na+].O=C3C(CCCC)C(=O)N(c1ccccc1)N3c2ccccc2
InChI: InChI=1/C19H20N2O2.Na/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16;/h4-13,17H,2-3,14H2,1H3;/q;+1
InChIKey: BSYZHKCQBROKHA-UHFFFAOYAB
Std. InChI: InChI=1S/C19H20N2O2.Na/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16;/h4-13,17H,2-3,14H2,1H3;/q;+1
Std. InChIKey: BSYZHKCQBROKHA-UHFFFAOYSA-N

Sodium butazolidine Uses

Sodium butazolidine (CAS NO.129-18-0) can be used for antipyretic analgesics for the treatment of rheumatic and rheumatoid arthritis and gout, etc.

Sodium butazolidine Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	169mg/kg (169mg/kg)		Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 314, 1970.
mouse	LD50	intravenous	94mg/kg (94mg/kg)		Farmaco, Edizione Scientifica. Vol. 13, Pg. 922, 1958.
mouse	LD50	oral	476mg/kg (476mg/kg)		Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 314, 1970.
mouse	LD50	subcutaneous	257mg/kg (257mg/kg)		Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 63, Pg. 43, 1967.
rabbit	LD50	intravenous	146mg/kg (146mg/kg)		Schweizerische Medizinische Wochenschrift. Vol. 84, Pg. 1315, 1954.
rat	LD50	intravenous	113mg/kg (113mg/kg)		Farmaco, Edizione Scientifica. Vol. 13, Pg. 922, 1958.
rat	LD50	oral	855mg/kg (855mg/kg)		Indian Journal of Physiology and Pharmacology. Vol. 5, Pg. 113, 1961.
rat	LD50	subcutaneous	310mg/kg (310mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 229, 1958.
women	LDLo	oral	16mg/kg/D (16mg/kg)	LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI BLOOD: AGRANULOCYTOSIS SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Annals of Internal Medicine. Vol. 39, Pg. 1096, 1953.

Sodium butazolidine Safety Profile

A human poison by ingestion. Human systemic effects by ingestion: respiratory system damage, agranulocytosis, and dermatitis. An experimental poison via subcutaneous, intravenous, and intraperitoneal routes. An anti-inflammatory drug. When heated to decomposition it emits toxic fumes of NO_x and Na₂O.

Sodium butazolidine Specification

Sodium butazolidine (CAS NO.129-18-0) also can be called 4-Butyl-1,2-diphenylpyrazolidine-3,5-dione, sodium salt and 3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-, monosodium salt .

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