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Chemical Baike

Hydroxylation at the 11th and 12th Positions

You will need to introduce hydroxyl groups at the 11th and 12th positions of arachidonic acid. This can be achieved through various methods, such as using a hydroxylating agent like OsO4, followed by reduction using a suitable reducing agent. This step will yield 11(S)-HETE and 12(S)-HETE.

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