In a dry and inert atmosphere (under nitrogen or argon), add the carboxylic acid (substrate) to the reaction vessel.
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Phentydrone
Diethyl ether
PyBOP
2-DIETHYLAMINOMETHYL-ACRYLIC ACID
2-Benzyl-3-((2R,5R)-2,5-bis-methoxymethoxymethyl-pyrrolidin-1-yl)-3-oxo-propionitrile
