Chemists may make structural modifications to the sulfonamide core, introducing functional groups or substituents that interact more favorably with the active site of CA I. This can involve the addition of ureido or thioureido groups.
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Benzenesulfonamide, 4-[2-[[(2-propenylamino)thioxomethyl]amino]ethyl]-
methyl (S)-2-(2-aminobenzamido)-2-phenylacetate
C41H74NO2PSSn2
(1R,cis)-3-<<2-amino-6-chloro-5-(4-chlorophenylazo)pyrimidin-4-yl>aminomethyl>-1,2,2-trimethylcyclopentylmethanol
Ethanone, 1-(2-chloro-1-cyclopenten-1-yl)-, O-(phenylmethyl)oxime, (1E)-
3-ALPHA-HYDROXY-6-OXO-5-ALPHA-CHOLAN-24-OIC ACID METHYL ESTER 3-ACETATE
tert-butyl{[(1S,5E)-6-{(3aR,4R,6aS)-2,2-dimethyl-4-[(trityloxy)methyl]tetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl}-1-methylhex-5-en-1-yl]oxy}diphenylsilane
(E,Z)-4-(1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl)phenyl trifluoromethanesulfonate
4
hydrogen peroxide
(1H-benzo[d][1,2,3]triazol-1-yl)(3,3-diphenyl-3H-benzo[f]chromen-8-yl)methanone
