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Cas Database |
| Name |
Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)- |
EINECS | N/A |
| CAS No. | 1334321-39-9 | Density | 1.296±0.06 g/cm3 (20 oC 760 Torr) |
| PSA | 95.86000 | LogP | 2.68650 |
| Solubility | (0.27 g/L) (25 oC) | Melting Point |
N/A |
| Formula | C17H27NO5 | Boiling Point | 497.3±20.0 °C(Predicted) |
| Molecular Weight | 325.405 | Flash Point | N/A |
| Transport Information | N/A | Appearance | White powder |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
(R)-N-Boc-2-(3-hydroxyadamant-1-yl)glycine;(alphaR)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-hydroxytricyclo[3.3.1.1(3,7)]decane-1-acetic acid; |
Article Data | 3 |
Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)- Specification
Boc-3-hydroxy-1-adamantyl-L-glycine is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
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(R)-N-Boc-3-hydroxyadaMantylglycine
