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1334321-39-9

Basic Information
CAS No.: 1334321-39-9
Name: (R)-N-Boc-3-hydroxyadaMantylglycine
Article Data: 3
Molecular Structure:
Molecular Structure of 1334321-39-9 ((R)-N-Boc-3-hydroxyadaMantylglycine)
Formula: C17H27NO5
Molecular Weight: 325.405
Synonyms: (R)-N-Boc-2-(3-hydroxyadamant-1-yl)glycine;(alphaR)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-hydroxytricyclo[3.3.1.1(3,7)]decane-1-acetic acid;
Density: 1.296±0.06 g/cm3 (20 oC 760 Torr)
Boiling Point: 497.3±20.0 °C(Predicted)
Solubility: (0.27 g/L) (25 oC)
Appearance: White powder
PSA: 95.86000
LogP: 2.68650
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Specification

Boc-3-hydroxy-1-adamantyl-L-glycine is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.