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102-65-8

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Basic Information
CAS No.: 102-65-8
Name: Sulfaclozine
Molecular Structure:
Molecular Structure of 102-65-8 (Sulfaclozine)
Formula: C10H9ClN4O2S
Molecular Weight: 284.726
Synonyms: Benzenesulfonamide,4-amino-N-(6-chloropyrazinyl)- (9CI);Sulfanilamide, N1-(6-chloropyrazinyl)-(7CI,8CI);Esb3 (antibiotic);N1-(6-Chloropyrazinyl)sulfanilamide;Sulfachloropyrazine;Sulfatyf;
EINECS: 203-044-0
Density: 1.588 g/cm3
Melting Point: 234.8-235.4 °C
Boiling Point: 495.7 °C at 760 mmHg
Flash Point: 253.6 °C
Solubility: soluble in water or methanol,slightly soluble in ethanol or acetone and not dissoluble in chloroform.
Appearance: Slightly yellow crystal powder
PSA: 106.35000
LogP: 3.24800
Related products
Synthetic route

N-(6-chloropyrazin-2-yl)-4-nitrobenzenesulfonamide

102-65-8

4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With tin(II) chloride dihdyrate In ethanol at 80℃; for 0.5h;81%
98-74-8

4-Nitrobenzenesulfonyl chloride

102-65-8

4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride; pyridine / acetone / 20 °C / Sealed tube
2: tin(II) chloride dihdyrate / ethanol / 0.5 h / 80 °C
View Scheme
2555-29-5

8-acetyl-7-hydroxy-4-methyl-2H-chromen-2-one

102-65-8

4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

C22H17ClN4O5S

Conditions
ConditionsYield
With acetic acid for 1h; Reflux;
102-65-8

4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

C21H19Cl2N5NiO8S

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: hydrogenchloride; sodium nitrite / water / Cooling with ice
1.2: 0.25 h / Cooling with ice
2.1: ammonium hydroxide / water; ethanol / Heating
View Scheme
102-65-8

4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

C42H30Cl2N10O12S2Zn

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: hydrogenchloride; sodium nitrite / water / Cooling with ice
1.2: 0.25 h / Cooling with ice
2.1: ammonium hydroxide / ethanol / Heating
View Scheme
102-65-8

4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

C21H15Cl2N5O6PdS

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: hydrogenchloride; sodium nitrite / water / Cooling with ice
1.2: 0.25 h / Cooling with ice
2.1: ammonium hydroxide / ethanol / Heating
View Scheme
102-65-8

4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

86-48-6

1-hydroxy-2-naphthoic acid

C21H14ClN5O5S

Conditions
ConditionsYield
Stage #1: 4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide With hydrogenchloride; sodium nitrite In water Cooling with ice;
Stage #2: 1-hydroxy-2-naphthoic acid With sodium hydroxide In water for 0.25h; Cooling with ice;
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    102-65-8

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    102-65-8

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Chemistry

IUPAC  Name: 4-Amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide   
Empirical Formula: C10H9ClN4O2S
Molecular Weight: 284.7221 
Einecs: 203-044-0 
Freely Rotating Bonds: 2
Polar Surface Area: 74.78 Å2
Index of Refraction: 1.683
Molar Refractivity: 67.97 cm3
Molar Volume: 179.2 cm3
Polarizability: 26.94 ×10-24 cm3
Surface Tension: 83.3 dyne/cm
Density: 1.588 g/cm3
Flash Point: 253.6 °C
Enthalpy of Vaporization: 76.33 kJ/mol
Boiling Point: 495.7 °C at 760 mmHg
Vapour Pressure: 5.77E-10 mmHg at 25°C 
The Cas Register Number of  Sulfaclozine is 102-65-8.The chemical synonyms of  Sulfaclozine (CAS NO.102-65-8) are N(sup 1)-(6-Chloropyrazinyl)sulfanilamide .The molecular structure of  Sulfaclozine (CAS NO.102-65-8) is
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Uses

 Sulfaclozine (CAS NO.102-65-8) is used in organic synthesis.