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CAS No.: | 14459-29-1 |
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Name: | HEMATOPORPHYRIN |
Article Data: | 12 |
Molecular Structure: | |
Formula: | C34H38 N4 O6 |
Molecular Weight: | 598.699 |
Synonyms: | 2,18-Porphinedipropionicacid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl- (8CI); Hematoporphyrin IX(6CI); 1,3,5,8-Tetramethyl-2,4-bis(a-hydroxyethyl)porphine-6,7-dipropionic acid;7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-2,18-porphinedipropionic acid;HP; Hematoporphyrin; HpIX; NSC 267084; NSC 59265; Photodyn |
Density: | 1.32g/cm3 |
Melting Point: | 172.5°C |
Boiling Point: | 1192.7°Cat760mmHg |
Flash Point: | 675.1°C |
Hazard Symbols: | Toxic. Reported to be preferentially absorbed by cancerous tissues, making them fluoresce under UV light. |
Safety: | Poison by intravenous route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. |
PSA: | 171.36000 |
LogP: | 2.64570 |
Conditions | Yield |
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Stage #1: hematoporphyrin With thionyl chloride Stage #2: cordycepin |
IUPAC Name: 3-[18-(2-Carboxyethyl)-7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid
Synonyms: 1,3,5,8-Tetramethyl-2,4-bis(alpha-hydroxyethyl)prophine-6,7-dipropionicacid ; 21H,23H-Porphine-2,18-dipropanoicacid,7,12-bis(1-hydroxyethyl)-3,8,13,17-te ; 7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-18-porphinedipropionicacid ; Hematoporphyrinix ;HP ; 8,13-Bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid ; Haematoporphyrin ; Hematoporphyrin
CAS NO: 14459-29-1
Molecular Formula: C34H38N4O6
Molecular Weight: 598.69
Molecular Structure:
EINECS: 238-450-7
Merck : 13,4653
Mol File: 14459-29-1.mol
Index of Refraction: 1.642
Surface Tension: 66.1 dyne/cm
Density: 1.328 g/cm3
Flash Point: 667.3 °C
Enthalpy of Vaporization: 182.92 kJ/mol
Boiling Point: 1179.7 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Storage temp: 2-8°C
Appearance: Photodyn (CAS NO.14459-29-1) is red purple crystal.
Solubility: Photodyn (CAS NO.14459-29-1) is soluble in ethanol, slightly soluble in ether and chloroform, insoluble in water.
Photodyn (CAS NO.14459-29-1) is used in biochemical research and clinical treatment for cancer.
Hemin (Hemin) in glacial acetic acid with treatment by hydrobromide ,then Photodyn (CAS NO.14459-29-1) is obtained.
1. | dnd-nml 100 µmol/L | CNREA8 Cancer Research. 41 (1981),3543. | ||
2. | dni-mus:leu 1 mg/L | TUMOAB Tumori. 67 (1981),183. | ||
3. | ivn-mus LD50:307 mg/kg | NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. 57 (1961),219. |
Poison by intravenous route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Safety Statements 22-24/25
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
WGK Germany 3
RTECS TS5500000
F 8-10-21