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192648-66-1

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Basic Information
CAS No.: 192648-66-1
Name: 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-[[2-(acetyloxy)benzoyl]oxy]-8-methyl-, methyl ester, (1R,2R,3S,5S)-
Article Data: 2
Molecular Structure:
Molecular Structure of 192648-66-1 (8-Azabicyclo[3.2.1]octane-2-carboxylic acid,
3-[[2-(acetyloxy)benzoyl]oxy]-8-methyl-, methyl ester, (1R,2R,3S,5S)-)
Formula: C19H23NO6
Molecular Weight: 361.395
Synonyms: 3-[(2'-acetoxybenzoyl)oxy]-[1R-(exo,exo)]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester;2'-Acetoxycocaine;
PSA: 82.14000
LogP: 1.73090
Synthetic route
7143-09-1

methyl ecgonine

5538-51-2

O-acetylsalicyloyl chloride

192648-66-1

3-[(2'-acetoxybenzoyl)oxy]-[1R-(exo,exo)]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With triethylamine In benzene at 40℃;
7143-09-1

methyl ecgonine

acetylsalicyloyl chloride

192648-66-1

3-[(2'-acetoxybenzoyl)oxy]-[1R-(exo,exo)]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With triethylamine In benzene at 40℃;
5796-31-6

ecgonine hydrochloride

192648-66-1

3-[(2'-acetoxybenzoyl)oxy]-[1R-(exo,exo)]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HCl gas
2: Et3N / benzene / 40 °C
View Scheme
50-36-2

Cocaine

192648-66-1

3-[(2'-acetoxybenzoyl)oxy]-[1R-(exo,exo)]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aq. HCl
2: HCl gas
3: Et3N / benzene / 40 °C
View Scheme
192648-66-1

3-[(2'-acetoxybenzoyl)oxy]-[1R-(exo,exo)]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With hydrogenchloride In methanol for 48h; Heating;94%
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  • methyl (3S,4R)-3-(2-acetyloxybenzoyl)oxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

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    192648-66-1

    methyl (3S,4R)-3-(2-acetyloxybenzoyl)oxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

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    Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

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  • methyl (3S,4R)-3-(2-acetyloxybenzoyl)oxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

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    192648-66-1

    methyl (3S,4R)-3-(2-acetyloxybenzoyl)oxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

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    FOB Price:  USD $ 0.0-0.0

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  • Casno:

    192648-66-1

    192648-66-1

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    Hebei Ruishun Trade Co.,Ltd registered capital one million, we have a production of pharmaceutical raw materials, pharmaceutical raw materials factory reagent r&d center, we do

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