CAS No.24345-16-2,Apamin Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	24345-16-2
Name:	Apamin

Formula:	C79H131 N31 O24 S4
Molecular Weight:	2027.65
Synonyms:	66: PN: WO2008088422 FIGURE: 8 claimed protein;68: PN:WO2006116156 SEQID: 68 claimed protein;Apamin (reduced), cyclic (1?;15)-bis(disulfide);Apamine;L-Histidinamide,L-cysteinyl-L-asparaginyl-L-cysteinyl-L-lysyl-L-alanyl-L-prolyl-L-a-glutamyl-L-threonyl-L-alanyl-L-leucyl-L-cysteinyl-L-alanyl-L-arginyl-L-arginyl-L-cysteinyl-L-glutaminyl-L-glutaminyl-,cyclic (1?;15)-bis(disulfide);
EINECS:	246-182-7
Density:	1.63
Boiling Point:	847.17°C (rough estimate)
Safety:	Poison by intravenous, parenteral, intracerebral, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of SO_x and NO_x.
PSA:	1021.52000
LogP:	-0.31540

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Chemistry

Molecular Formula: C₇₉H₁₃₁O₂₄S₄
Molecular Weight: 2027.65g/mol
EINECS: 246-182-7
Freely Rotating Bonds: 38
Polar Surface Area: 1021.52 Å²
Index of Refraction: 1.724
Molar Refractivity: 491.235 cm³
Molar Volume: 1238.918 cm³
Polarizability: 194.741× 10^-24cm³
Surface Tension: 77.455 dyne/cm
Density: 1.636 g/cm³
The Cas Register Number of Apamin is 24345-16-2 .The chemical synonyms of Apamin (CAS No.24345-16-2) are H-+cys-asn-++cys-lys-ala-pro-glu-thr-ala-leu-+cys-ala-arg-arg-++cys-gln-gln- his-nh2 ; H-Cys-asn-cys-lys-ala-pro-glu-thr-ala-leu-cys-ala-arg-arg-cys-gln-gln-his-nh2 ; H-Cys-asn-cys-lys-ala-pro-glu-thr-ala-leu-cys-ala-arg-arg-cys-gln-gln-his-nh2 (disulfide bridge: 1-11, 3-15) ; Cys-asn-cys-lys-ala-pro-glu-thr-ala-leu-cys-ala-arg-arg-cys-gln-gln-his-nh2 ; Cys-asn-cys-lys-ala-pro-glu-thr-ala-leu-cys-ala-arg-cys-gln-gln-his-nh2 ; [Cys-asn-(cys-lys-ala-pro-glu-thr-ala-leu-cys]cycl-ala-arg-arg-cys)cycl-gln-gln-his-nh2 ; Cnckapetalcarrcqqh-nh2 ; Cnckapetalcarrcqqh-nh2 (disulfide bridge: 1-11,3-15) .Product categories of Apamin (CAS No.24345-16-2) are Peptide ; Beevoltage-gated ion channels ; Cell signaling and neuroscience ; Ion channel modulating peptides ; Monovalent ion channels ; Potassium channel modulators ; Potassium channel modulatorspeptides for cell biology ; Toxins and venoms ; Potassium channel .The molecular structure of Apamin (CAS No.24345-16-2) is.

Uses

It can be used in organic synthesis.

Toxicity Data With Reference

1.	ipr-mus LD50:3800 µg/kg	TOXIA6 Toxicon. 22 (1984),308.
2.	ivn-mus LD50:4 mg/kg	NSAPCC Naunyn-Schmiedeberg’s Archives of Pharmacology. 300 (1977),189.
3.	ice-mus LD50:1800 ng/kg	TOXIA6 Toxicon. 22 (1984),308.
4.	par-mus LD50:600 mg/kg	TOXIA6 Toxicon. 20 (1982),157.

Safety Profile

Poison by intravenous, parenteral, intracerebral, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of SO_x and NO_x.
Safety Statements: 22-24/25
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
RIDADR: 2811
WGK Germany: 3
RTECS: CD6899900
F: 3-10
HazardClass: 6.1(b)
PackingGroup: III