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25519-80-6

Basic Information
CAS No.: 25519-80-6
Name: 4-BENZOYLPIPERIDINE HYDROCHLORIDE
Article Data: 4
Molecular Structure:
Molecular Structure of 25519-80-6 (4-BENZOYLPIPERIDINE HYDROCHLORIDE)
Formula: C12H15 N O . Cl H
Molecular Weight: 225.718
Synonyms: Ketone,phenyl 4-piperidyl, hydrochloride (8CI); Methanone, phenyl-4-piperidinyl-,hydrochloride (9CI); 4-Benzoylpiperidine hydrochloride;Phenyl(piperidin-4-yl)methanone hydrochloride
Density: g/cm3
Melting Point: 95-97oC
Boiling Point: 310.7°Cat760mmHg
Flash Point: 125.3°C
Hazard Symbols: Xi
PSA: 29.10000
LogP: 2.99970
Synthetic route
193217-39-9

1-(t-butoxycarbonyl)-4-(benzoyl)piperidine

25519-80-6

4-(benzoyl)piperidine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane at 18 - 25℃; for 0.5h;98%
With hydrogenchloride In 1,4-dioxane
25519-79-3

1-(4-benzoylpiperidin-1-yl)ethanone

25519-80-6

4-(benzoyl)piperidine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; water In tetrahydrofuran for 10h; Reflux;
25503-90-6

1-acetyl-piperidine-4-carboxylic acid

25519-80-6

4-(benzoyl)piperidine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: thionyl chloride; N,N-dimethyl-formamide / 1,2-dichloro-ethane / 4 h / 0 - 60 °C
2: aluminum (III) chloride / 1,2-dichloro-ethane / 16 h / 0 - 65 °C
3: hydrogenchloride; water / tetrahydrofuran / 10 h / Reflux
View Scheme
498-94-2

isonipecotic acid

25519-80-6

4-(benzoyl)piperidine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: pyridine / 2 h / 140 °C
2: thionyl chloride; N,N-dimethyl-formamide / 1,2-dichloro-ethane / 4 h / 0 - 60 °C
3: aluminum (III) chloride / 1,2-dichloro-ethane / 16 h / 0 - 65 °C
4: hydrogenchloride; water / tetrahydrofuran / 10 h / Reflux
View Scheme
59084-16-1

1-acetylpiperidine-4-carbonyl chloride

25519-80-6

4-(benzoyl)piperidine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aluminum (III) chloride / 1,2-dichloro-ethane / 16 h / 0 - 65 °C
2: hydrogenchloride; water / tetrahydrofuran / 10 h / Reflux
View Scheme
501-53-1

benzyl chloroformate

25519-80-6

4-(benzoyl)piperidine hydrochloride

922504-27-6

4-benzoylpiperidine-1-carboxylic acid benzyl ester

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 0 - 20℃; for 2h;100%
With potassium carbonate In tetrahydrofuran at 0 - 25℃; for 15h; Inert atmosphere;97.76%
With potassium carbonate In tetrahydrofuran at 0 - 20℃; for 2h;90%
With potassium carbonate In 1,4-dioxane; water Cooling with ice;1.43 g
24424-99-5

di-tert-butyl dicarbonate

25519-80-6

4-(benzoyl)piperidine hydrochloride

193217-39-9

1-(t-butoxycarbonyl)-4-(benzoyl)piperidine

Conditions
ConditionsYield
With potassium hydrogencarbonate In tetrahydrofuran; water for 1h; Condensation; Heating;98%
With sodium carbonate In tetrahydrofuran; water for 1h; Heating;98%
With potassium hydrogencarbonate In H2 O-TBF98%
25519-80-6

4-(benzoyl)piperidine hydrochloride

137049-00-4

1-methyl-1H-imidazole-4-sulfonyl chloride

1246526-78-2

(1-(1-Methyl-1H-Imidazol-4-ylsulfonyl)Piperidin-4-yl)(Phenyl)Methanone

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane for 18h;93%
138608-95-4

2-(benzylthio)-4-(4-methoxyphenyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile

25519-80-6

4-(benzoyl)piperidine hydrochloride

1425974-12-4

C31H28N4O2S

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; for 12h;70%
25519-80-6

4-(benzoyl)piperidine hydrochloride

2-Benzylsulfanyl-4-(4-chloro-phenyl)-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile

1425974-03-3

C30H25ClN4OS

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; for 12h;64%
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  • 4-benzoylpiperidine hydrochloride

  • Casno:

    25519-80-6

    4-benzoylpiperidine hydrochloride

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen

    Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four years Our key scienti

  • Debye Scientific

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+85221376140

    Address:Rm. 19C, Lockhart Ctr., 301-307 Lockhart Rd., Wan Chai

       Inquiry Now

  • Phenyl(4-piperidinyl)methanone HCl

  • Casno:

    25519-80-6

    Phenyl(4-piperidinyl)methanone HCl

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    high purity Application:Drug intermediates Materials intermediates and active molecules

    Novachemistry offers a broad range of specialty chemicals and customized synthesis services to a range of pharmaceutical, agrochemical and biochemical industries. Novachemistry has

  • NovaChemistry

    United Kingdom  |  Contact Details

    Business Type:Trading Company

    Tel:+44 (0)208 191 7890

    Address:Unit11, Ark Business Centre, Gorden Road, Loughborough, United Kingdom

       Inquiry Now

  • 4-Benzoylpiperidine hydrochloride

  • Casno:

    25519-80-6

    4-Benzoylpiperidine hydrochloride

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    DR PREM’S MOLECULES PRIVATE LIMITED (DPMolecules) is a specialty chemical store for the pharmaceutical industry. Its supplies come from its fully owned manufacturing company SYNTH

  • Dr.Prem's Molecules

    India  |  Contact Details

    Business Type:Trading Company

    Tel:0091-9825310038

    Address:102 Chaitanya apts., 7 Laxmi colony,Near Urmi Char Rasta

       Inquiry Now

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