Products Categories
CAS No.: | 30459-70-2 |
---|---|
Name: | 2-Methyl-4-nitrobenzoyl chloride |
Article Data: | 19 |
Molecular Structure: | |
Formula: | C8H6ClNO3 |
Molecular Weight: | 199.594 |
Synonyms: | Benzoyl chloride,2-methyl-4-nitro;2-Methyl-4-nitro-benzoylchlorid;4-nitro-2-methyl-benzoylchloride;2-methyl-4-nitro-benzoic acid chloride;2-methyl-4-nitro-benzoyl chloride; |
Density: | 1.386±0.06 g/cm3(Predicted) |
Melting Point: | 34 °C |
Boiling Point: | 149-153 °C(Press: 14 Torr) |
PSA: | 62.89000 |
LogP: | 2.80540 |
2-methyl-4-nitrobenzoic acid
2-methyl-4-nitrobenzoyl chloride
Conditions | Yield |
---|---|
With thionyl chloride | |
With thionyl chloride Heating; | |
With thionyl chloride Substitution; |
Conditions | Yield |
---|---|
In dichloromethane at 0℃; for 0.5h; | 100% |
In dichloromethane at 0℃; for 0.5h; | 100% |
2,2-dimethylpropionic acid 7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester
2-methyl-4-nitrobenzoyl chloride
2,2-dimethylpropionic acid 7-chloro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 1h; | 98% |
With triethylamine In dichloromethane at 0 - 20℃; for 1.25h; | 98% |
2,2-dimethylpropionic acid 7-fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester
2-methyl-4-nitrobenzoyl chloride
2,2-dimethylpropionic acid 7-fluoro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 1h; | 97% |
2-methyl-4-nitrobenzoyl chloride
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
1-(4-nitro-2-methylbenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
Stage #1: 7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one With magnesium hydroxide In acetonitrile at 10℃; for 0.5h; Stage #2: 2-methyl-4-nitrobenzoyl chloride In acetonitrile for 5h; | 95% |
With sodium hydroxide In acetonitrile at 20℃; for 1h; | 73% |
With triethylamine In dichloromethane at 20℃; for 2h; Acylation; | 32% |
2-methyl-4-nitrobenzoyl chloride
7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepine
(7-chloro-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)-2-methyl-4-nitrobenzamide
Conditions | Yield |
---|---|
With pyridine In dichloromethane for 1h; | 91% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 4h; Reagent/catalyst; | 88.7% |
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 3h; Reagent/catalyst; | 88% |
2-methyl-4-nitrobenzoyl chloride
methyl 4-(2-amino-5-chlorophenyl)-4-oxobutyrate
C19H17ClN2O6
Conditions | Yield |
---|---|
With pyridine In dichloromethane | 87% |
L-glutamic acid diethyl ester
2-methyl-4-nitrobenzoyl chloride
diethyl N-(2-methyl-4-nitrobenzoyl)-L-glutamate
Conditions | Yield |
---|---|
With pyridine In toluene at 0 - 25℃; for 1.5h; | 77% |