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CAS No.: | 31375-19-6 |
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Name: | Pyrimido[4,5-d]pyrimidine, 1,5-dihydro-2-methyl- (6CI,8CI,9CI) |
Article Data: | 4 |
Molecular Structure: | |
Formula: | C7H8 N4 |
Molecular Weight: | 148.167 |
Synonyms: | Pyrimido[4,5-d]pyrimidine,1,5-dihydro-2-methyl- (6CI,8CI,9CI); |
Density: | 1.397g/cm3 |
Melting Point: | 173 °C (decomp) |
Boiling Point: | 277.008°C at 760 mmHg |
Flash Point: | 121.33°C |
PSA: | 50.17000 |
LogP: | 0.31240 |
5-(aminomethyl)-2-methylpyrimidin-4-amine
N,N-dimethyl-formamide dimethyl acetal
3,4-Dihydro-7-methylpyrimido<4,5-d>pyrimidine
Conditions | Yield |
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1.) 80 to 85 deg C, 2.) 90 deg C, 30 min; | 88.5% |
5-(aminomethyl)-2-methylpyrimidin-4-amine
orthoformic acid triethyl ester
3,4-Dihydro-7-methylpyrimido<4,5-d>pyrimidine
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid Heating; | 71% |
pyridine
4-Amino-2-methyl-5-thioformamidomethylpyrimidin
3,4-Dihydro-7-methylpyrimido<4,5-d>pyrimidine
4-Amino-2-methyl-5-thioformamidomethylpyrimidin
3,4-Dihydro-7-methylpyrimido<4,5-d>pyrimidine
Conditions | Yield |
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With pyridine |
5-(aminomethyl)-2-methylpyrimidin-4-amine
3,4-Dihydro-7-methylpyrimido<4,5-d>pyrimidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: H2O 2: pyridine View Scheme |
3,4-Dihydro-7-methylpyrimido<4,5-d>pyrimidine
3-Mercapto-4-oxopentyl Acetate
Thiamine formate
Conditions | Yield |
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With formic acid for 0.5h; Ambient temperature; | 89.3% |
3,4-Dihydro-7-methylpyrimido<4,5-d>pyrimidine
2-methyl-4-amino-5-formylaminomethylpyrimidine
Conditions | Yield |
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an der Luft erfolgt; |
3,4-Dihydro-7-methylpyrimido<4,5-d>pyrimidine
3-Mercapto-4-oxopentyl Acetate
Thiamine hydrochloride
Conditions | Yield |
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With hydrogenchloride; formic acid 1.) 30 min, RT, 2.) EtOH, 30 min, RT; Yield given. Multistep reaction; |