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CAS No.: | 3758-59-6 |
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Name: | 4-Pyridinecarboxylic acid, 2-methyl-, hydrazide |
Article Data: | 16 |
Molecular Structure: | |
Formula: | C7H9 N3 O |
Molecular Weight: | 151.168 |
Synonyms: | Isonicotinicacid, 2-methyl-, hydrazide (6CI,7CI,8CI); 2-Methylisonicotinic acid hydrazide;2-Methylisonicotinoylhydrazine; NSC 280609 |
Density: | 1.195g/cm3 |
Boiling Point: | °Cat760mmHg |
Flash Point: | °C |
PSA: | 68.01000 |
LogP: | 1.08470 |
methyl 2-methylisonicotinate
2-methylisonicotinohydrazide
Conditions | Yield |
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With hydrazine In methanol at 20℃; for 18h; | 86% |
With ethanol; hydrazine hydrate | |
With methanol; hydrazine hydrate |
2-chloro-6-methylisonicotinohydrazide
2-methylisonicotinohydrazide
Conditions | Yield |
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With sodium hydroxide; palladium Hydrogenation; | |
With hydrogen; triethylamine; palladium 10% on activated carbon In ethanol at 20℃; |
2-hydroxy-6-methylpyridine-4-carboxylic acid
2-methylisonicotinohydrazide
Conditions | Yield |
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Multi-step reaction with 3 steps 1: POCl3; PCl5 / Behandeln des Reaktionsprodukts mit Methanol 2: palladium/charcoal; methanol; potassium acetate / Hydrogenation 3: methanol; N2H4+H2O View Scheme |
Conditions | Yield |
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Multi-step reaction with 2 steps 1: palladium/charcoal; methanol; potassium acetate / Hydrogenation 2: methanol; N2H4+H2O View Scheme |
Conditions | Yield |
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With 1,1'-carbonyldiimidazole; hydrazine In tetrahydrofuran at 20℃; | |
Stage #1: 2-methylisonicotinic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 20℃; for 1h; Stage #2: With hydrazine In tetrahydrofuran at 20℃; for 6h; |
ethyl 2-methylpyridine-4-carboxylate
2-methylisonicotinohydrazide
Conditions | Yield |
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With hydrazine hydrate In ethanol for 12h; Reflux; |
2-methylisonicotinohydrazide
Conditions | Yield |
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In isopropyl alcohol at 90℃; for 24h; | 55% |
2-methylisonicotinohydrazide
Conditions | Yield |
---|---|
In isopropyl alcohol at 90℃; for 24h; | 47% |
2-methylisonicotinohydrazide
2-formylbenzene boronic acid
Conditions | Yield |
---|---|
In isopropyl alcohol at 20℃; | 22% |
2-methylisonicotinohydrazide
Conditions | Yield |
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With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 16h; | 12% |