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38969-40-3

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Basic Information
CAS No.: 38969-40-3
Name: ECGONINE METHYL ESTER HYDROCHLORIDE
Article Data: 3
Molecular Structure:
Molecular Structure of 38969-40-3 (ECGONINE METHYL ESTER HYDROCHLORIDE)
Formula: C10H18ClNO3
Molecular Weight: 235.711
Synonyms: (-)-Ecgonine Methyl Ester Hydrochloride;ECGONINE METHYL ESTER HCL;
Density: g/cm3
Boiling Point: 305.8°Cat760mmHg
Flash Point: 138.7°C
PSA: 49.77000
LogP: 0.74290
Synthetic route
53-21-4

(-)-cocaine hydrochloride

38969-40-3

Ecgonine methyl ester hydrochloride

Conditions
ConditionsYield
With hydrogenchloride for 15h; Heating; Yield given;
67-56-1

methanol

5796-31-6

ecgonine hydrochloride

38969-40-3

Ecgonine methyl ester hydrochloride

Conditions
ConditionsYield
With hydrogenchloride
53-21-4

(-)-cocaine hydrochloride

aqueous solution

aqueous solution

38969-40-3

Ecgonine methyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.25M aq. HCl / Heating
2: HCl
View Scheme
38969-40-3

Ecgonine methyl ester hydrochloride

481-37-8

ecgonine

Conditions
ConditionsYield
With phosphate buffer In water at 30℃; Kinetics; other reagents;
38969-40-3

Ecgonine methyl ester hydrochloride

7143-09-1

methyl ecgonine

Conditions
ConditionsYield
In methanol; diethyl ether Yield given;
50972-25-3

C13H12ClO2P

38969-40-3

Ecgonine methyl ester hydrochloride

148533-52-2

(1R,2R,3S,5S)-methyl 3-(((benzyloxy)(phenyl)phosphoryl)oxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate

Conditions
ConditionsYield
Stage #1: Ecgonine methyl ester hydrochloride With lithium diisopropyl amide
Stage #2: C13H12ClO2P
38969-40-3

Ecgonine methyl ester hydrochloride

148533-51-1

(1R,2R,3S,5S)-methyl 3-(((benzyloxy)(phenyl)phosphoryl)oxy)-8-azabicyclo[3.2.1]octane-2-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: LDA
2.1: Troc-Cl; Et3N
2.2: Zn; HCO2H
View Scheme
38969-40-3

Ecgonine methyl ester hydrochloride

(1R,2R,3S,5S)-3-(Benzyloxy-phenyl-phosphinoyloxy)-8-(5-carboxy-pentyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: LDA
2.1: Troc-Cl; Et3N
2.2: Zn; HCO2H
3.1: Et3N / acetonitrile
4.1: TFA
View Scheme
38969-40-3

Ecgonine methyl ester hydrochloride

(1R,2R,3S,5S)-8-[5-(2-Carboxy-ethylcarbamoyl)-pentyl]-3-(hydroxy-phenyl-phosphinoyloxy)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: LDA
2.1: Troc-Cl; Et3N
2.2: Zn; HCO2H
3.1: Et3N / acetonitrile
4.1: TFA
5.1: EDC; HOBt
6.1: H2 / Pd/C
View Scheme
38969-40-3

Ecgonine methyl ester hydrochloride

148533-53-3

(1R,2R,3S,5S)-3-(Benzyloxy-phenyl-phosphinoyloxy)-8-(5-tert-butoxycarbonyl-pentyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: LDA
2.1: Troc-Cl; Et3N
2.2: Zn; HCO2H
3.1: Et3N / acetonitrile
View Scheme
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