Products Categories
CAS No.: | 4672-49-5 |
---|---|
Name: | ethylene dimethanesulfonate |
Article Data: | 26 |
Molecular Structure: | |
Formula: | C4H10O6S2 |
Molecular Weight: | 218.252 |
Synonyms: | 1,2-Ethanediol, dimethanesulfonate (9CI);Ethylene glycol, dimethanesulfonate (7CI,8CI);Methanesulfonic acid, ethylene ester (6CI);1,2-Bis(mesyloxy)ethane;1,2-Bis(methanesulfonyloxy)ethane;1,2-Bis(methylsulfonyloxy)ethane;1,2-Ethanediyl dimethanesulfonate;Ethane dimethanesulfonate;Ethylene bis(methanesulfonate);Ethylene glycol dimesylate;NSC 10716;NSC 17016; |
Density: | 1.461 g/cm3 |
Melting Point: | 35-36 °C |
Boiling Point: | 448.914 °C at 760 mmHg |
Flash Point: | 225.295 °C |
PSA: | 103.50000 |
LogP: | 1.10040 |
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; for 3h; | 96% |
In tetrahydrofuran at 20℃; for 4h; Cooling with ice; | 94% |
With triethylamine In dichloromethane at 0 - 20℃; | 89% |
Conditions | Yield |
---|---|
With tetraethylammonium bromide |
methanesulfonic acid
2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclopentadecin
A
1,2-bis(methanesulfonyloxy)ethane
B
diethylene glycol dimesylate
C
1,2-bis<(methylsulfonyl)oxy>benzene
Conditions | Yield |
---|---|
With phosphorus pentoxide |
Conditions | Yield |
---|---|
With sodium hydroxide In N,N-dimethyl-formamide at 90 - 120℃; for 4h; |
Conditions | Yield |
---|---|
Stage #1: (S)-N-(tert-butoxycarbonyl)tyrosine methyl ester With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 0.5h; Inert atmosphere; Stage #2: 1,2-bis(methanesulfonyloxy)ethane In tetrahydrofuran; mineral oil for 4h; Inert atmosphere; Reflux; | 93% |
Conditions | Yield |
---|---|
In acetonitrile at 80℃; for 72h; Inert atmosphere; | 90.4% |
1,2-bis(methanesulfonyloxy)ethane
2-methoxy-phenol
1,2-bis(2’-methoxyphenoxy)ethane
Conditions | Yield |
---|---|
Stage #1: 2-methoxy-phenol With caesium carbonate In acetonitrile at 20℃; for 3h; Inert atmosphere; Reflux; Stage #2: 1,2-bis(methanesulfonyloxy)ethane In acetonitrile for 24h; Inert atmosphere; Reflux; | 90% |
Conditions | Yield |
---|---|
at 60℃; for 48h; | 88% |
1,2-bis(methanesulfonyloxy)ethane
(R,R)-N,N'-(Cyclohexane-1,2-diyl)-N,N',N'',N'''-tetrakis(p-toluenesulfonyl)bis(3-oxapentane-1,5-diamine)
(1R,18R)-2,8,11,17-Tetrakis(p-toluenesulfonyl)-5,14-dioxa-2,8,11,17-tetraazabicyclo[16.4.0]docosane
Conditions | Yield |
---|---|
With caesium carbonate In acetonitrile for 96h; Cyclization; Substitution; Heating; | 87% |
1,2-bis(methanesulfonyloxy)ethane
dimethyl 1-benzyl-3,4-dihydroxypyrrole-2,5-dicarboxylate
dimethyl 1-benzyl-3,4-ethylenedioxypyrrole-2,5-dicarboxylate
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 130℃; for 8h; | 86% |
What can I do for you?
Get Best Price
The Ethylene dimethanesulfonate, with the CAS registry number 4672-49-5, is also known as 1,2-Bis(methylsulfonyloxy)ethane. This chemical's molecular formula is C4H10O6S2 and molecular weight is 218.25. What's more, its systematic name is 1,2-Ethanediyl dimethanesulfonate. Its classification code is Reproductive Effect. This chemical is used as an antispermatogenic agent.
Physical properties of Ethylene dimethanesulfonate are: (1)ACD/LogP: -0.79; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.79; (4)ACD/LogD (pH 7.4): -0.79; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 8.86; (8)ACD/KOC (pH 7.4): 8.86; (9)#H bond acceptors: 6; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 103.5 Å2; (13)Index of Refraction: 1.47; (14)Molar Refractivity: 41.68 cm3; (15)Molar Volume: 149.352 cm3; (16)Polarizability: 16.523×10-24cm3; (17)Surface Tension: 49.9 dyne/cm; (18)Density: 1.461 g/cm3; (19)Flash Point: 225.295 °C; (20)Enthalpy of Vaporization: 68.03 kJ/mol; (21)Boiling Point: 448.914 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)SMILES: O=S(=O)(OCCOS(=O)(=O)C)C
(2)Std. InChI: InChI=1S/C4H10O6S2/c1-11(5,6)9-3-4-10-12(2,7)8/h3-4H2,1-2H3
(3)Std. InChIKey: QSQFARNGNIZGAW-UHFFFAOYSA-N
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 250mg/kg (250mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 85, Pg. 211, 1954. | |
rat | LD50 | intraperitoneal | 150mg/kg (150mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 24, Pg. 24, 1965. |