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CAS No.: | 4778-96-5 |
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Name: | (5alpha,6alpha)-17-(2-phenylethyl)-4,5-epoxymorphinan-3,6,14-triol |
Article Data: | 3 |
Molecular Structure: | |
Formula: | C24H27NO4 |
Molecular Weight: | 393.483 |
Synonyms: | Normorphine,7,8-dihydro-14-hydroxy-N-phenethyl;7,8-Dihydro-14-hydroxy-N-phenethylnormorphine;RAM-378; |
Density: | 1.42g/cm3 |
Boiling Point: | 604.9°Cat760mmHg |
Flash Point: | 319.6°C |
PSA: | 73.16000 |
LogP: | 2.08780 |
4,5α-epoxy-3-methoxy-17-phenethyl-morphinane-6α,14-diol
4,5α-epoxy-17-phenethyl-morphinane-3,6α,14-triol
Conditions | Yield |
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With boron tribromide In chloroform at 0 - 5℃; for 1h; | 63% |
beta-Noroxycodol
4,5α-epoxy-17-phenethyl-morphinane-3,6α,14-triol
Conditions | Yield |
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Multi-step reaction with 2 steps 1: 56 percent / NaHCO3 / dimethylformamide / 20 h / 70 °C 2: 63 percent / BBr3 / CHCl3 / 1 h / 0 - 5 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 56 percent / NaHCO3 / dimethylformamide / 20 h / 70 °C 2: 63 percent / BBr3 / CHCl3 / 1 h / 0 - 5 °C View Scheme |
C22H24N2O6
4,5α-epoxy-17-phenethyl-morphinane-3,6α,14-triol
Conditions | Yield |
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Multi-step reaction with 3 steps 1: 10percent aq. HCl / 16 h / Heating 2: 56 percent / NaHCO3 / dimethylformamide / 20 h / 70 °C 3: 63 percent / BBr3 / CHCl3 / 1 h / 0 - 5 °C View Scheme |
C24H27NO8
4,5α-epoxy-17-phenethyl-morphinane-3,6α,14-triol
Conditions | Yield |
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Multi-step reaction with 3 steps 1: HCl gas / CH2Cl2 / 1 h 2: 56 percent / NaHCO3 / dimethylformamide / 20 h / 70 °C 3: 63 percent / BBr3 / CHCl3 / 1 h / 0 - 5 °C View Scheme |
6α,14β-diacetoxy-4,5percenta-epoxy-3-methoxy-17-methyl-morphinan
4,5α-epoxy-17-phenethyl-morphinane-3,6α,14-triol
Conditions | Yield |
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Multi-step reaction with 4 steps 1: 95 percent / CHCl3 / 16 h / Heating 2: 10percent aq. HCl / 16 h / Heating 3: 56 percent / NaHCO3 / dimethylformamide / 20 h / 70 °C 4: 63 percent / BBr3 / CHCl3 / 1 h / 0 - 5 °C View Scheme | |
Multi-step reaction with 4 steps 1: 70 percent / NaHCO3 / 1,2-dichloro-ethane 2: HCl gas / CH2Cl2 / 1 h 3: 56 percent / NaHCO3 / dimethylformamide / 20 h / 70 °C 4: 63 percent / BBr3 / CHCl3 / 1 h / 0 - 5 °C View Scheme |