CAS No.489-84-9,Guaiazulene Suppliers

Products Categories

Pharmaceutical (92)
Organic Chemicals (27)
Plant Extract (13)
Others (12)
Reagent (8)
Materials (3)
Agrochemicals (1)
Food Additives (1)
Synthetic Flavours & Fragrances (1)

Basic Information

Molecular Structure:
CAS No.:	489-84-9
Name:	Guaiazulene
Article Data:	93

Formula:	C15H18
Molecular Weight:	198.308
Synonyms:	Azulene,7-isopropyl-1,4-dimethyl- (8CI); 1,4-Dimethyl-7-(1-methylethyl)Azulene;1,4-Dimethyl-7-isopropylazulene; 3,8-Dimethyl-5-(2-propyl)azulene;7-Isopropyl-1,4-dimethylazulene; AZ 8; AZ 8 Beris; Azulen-Beris; Azulon;Azunol; Cuteazul; Eucazulen; Guaiazulene; Guaiazulene blue; Kessazulen; NSC4714; Purazulen; S-Guaiazulene; Silazulon; Uroazulen; Vaumigan; Vetivazulen
EINECS:	207-701-2
Density:	0.976
Melting Point:	28 - 30 C
Boiling Point:	153 °C7 mm Hg(lit.)
Flash Point:	113 ºC
Solubility:		dark blue semi-solid
Hazard Symbols:
Risk Codes:	R22
Safety:	Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes.
Transport Information:	20kgs
PSA:	0.00000
LogP:	4.53160

Synthetic route

: 1203707-11-2
1,1-bis{4-[2-(dimethylamino)ethoxy]phenyl}-2-(3-guaiazulenyl)ethylene

: 275-51-4
azulene

A: 489-84-9
7-isopropyl-1,4-dimethyl-azulene

B: 1314045-03-8
2-(azulen-1-yl)-1,1-bis{4-[2-(dimethylamino)ethoxy]phenyl}ethylene

Conditions

Conditions	Yield
With hydrogenchloride In methanol; water; acetonitrile at 60℃; for 3h;	A 97% B 58%

...Expand

: 867380-19-6
1-chloro-7-isopropyl-4-methyl-azulene

: 13061-96-6
dihydroxy-methyl-borane

: 489-84-9
7-isopropyl-1,4-dimethyl-azulene

Conditions

Conditions	Yield
With palladium diacetate; potassium phosphate In toluene at 100℃; for 24h;	94%

: 275-51-4
azulene

: 741737-71-3
1,1-bis[4-(methoxy)phenyl]-2-(3-guaiazulenyl)ethylene

A: 489-84-9
7-isopropyl-1,4-dimethyl-azulene

B: 1314045-02-7
1,3-bis[2,2-bis(4-methoxyphenyl)ethenyl]azulene

C: 2-(azulen-1-yl)-1,1-bis(4-methoxyphenyl)ethylene

Conditions

Conditions	Yield
With hydrogenchloride In methanol; water; acetonitrile at 60℃; for 3h;	A 93% B 19% C 34%

...Expand

: 1103995-55-6
1,1-bis[4-(dimethylamino)phenyl]-2-(3-guaiazulenyl)ethylene

: 275-51-4
azulene

A: 489-84-9
7-isopropyl-1,4-dimethyl-azulene

B: 1314044-93-3
2-(azulen-1-yl)-1,1-bis[4-(dimethylamino)phenyl]ethylene

C: 1314044-97-7
1,1-di(azulen-1-yl)-2,2-bis[4-(dimethylamino)phenyl]ethane

D: 1314044-96-6
1,3-bis{2,2-bis[4-(dimethylamino)phenyl]ethenyl}azulene

Conditions

Conditions	Yield
With hydrogenchloride In methanol; water; acetonitrile at 60℃; for 3h;	A 91% B 46% C 13% D 19%

...Expand

: dimethyl 3-isopropyl-6,11-dimethyltricyclo<6.2.2.01,7>dodeca-2,4,6,9,11-pentaene-9,10-dicarboxylate

A: 489-84-9
7-isopropyl-1,4-dimethyl-azulene

B: 98525-07-6, 72898-39-6, 98525-12-3, 98525-13-4
dimethyl 1,6-dimethyl-9-(1-methylethyl)heptalene-4,5-dicarboxylate

Conditions

Conditions	Yield
In acetonitrile at 110℃; for 1h;	A 29% B 71%
In acetonitrile at 100℃; for 1h; in sealed tube;	A 29% B 71%

: 3-bromoguaiazulenium bromide

A: 489-84-9
7-isopropyl-1,4-dimethyl-azulene

B: 17509-79-4
2,2'-biguaiazulenyl

Conditions

Conditions	Yield
With methanol Title compound not separated from byproducts;	A 50% B 20%

: 64-17-5
ethanol

: 10487-58-8
bis(3,8-dimethyl-5-isopropyl-1-azulenyl) ketone

A: 489-84-9
7-isopropyl-1,4-dimethyl-azulene

B: 81920-91-4
ethyl 3,8-dimethyl-5-isopropylazulene-1-carboxylate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid for 0.166667h; Heating;
With toluene-4-sulfonic acid for 0.166667h; Mechanism; Heating; regioselectivity; other substrates;

...Expand

: 64-17-5
ethanol

: 150985-85-6
Azulen-1-yl-(5-isopropyl-3,8-dimethyl-azulen-1-yl)-methanone

A: 489-84-9
7-isopropyl-1,4-dimethyl-azulene

B: 1206-88-8
ethyl azulene-1-carboxylate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid for 6h; Heating;

...Expand

: 64-17-5
ethanol

: 150985-81-2
(5-Isopropyl-3,8-dimethyl-azulen-1-yl)-(4,6,8-trimethyl-azulen-1-yl)-methanone

A: 489-84-9
7-isopropyl-1,4-dimethyl-azulene

B: 81920-91-4
ethyl 3,8-dimethyl-5-isopropylazulene-1-carboxylate

C: 4,6,8-Trimethyl-azulene-1-carboxylic acid ethyl ester

D: 275-51-4
azulene

Conditions

Conditions	Yield
With toluene-4-sulfonic acid for 0.166667h; Heating;

...Expand

: 64-17-5
ethanol

: 150985-82-3
1-[3-(5-Isopropyl-3,8-dimethyl-azulene-1-carbonyl)-4,6,8-trimethyl-azulen-1-yl]-ethanone

A: 489-84-9
7-isopropyl-1,4-dimethyl-azulene

B: 834-97-9
1-acetyl-4,6,8-trimethylazulene

C: 81920-91-4
ethyl 3,8-dimethyl-5-isopropylazulene-1-carboxylate

D: 3-Acetyl-4,6,8-trimethyl-azulene-1-carboxylic acid ethyl ester

Conditions

Conditions	Yield
With toluene-4-sulfonic acid for 1h; Heating;

...Expand

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:126 Page 1 of 4 1 2 3 4 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 489-84-9

Chemistry

Chemical Name: Guaiazulene
IUPAC NAME: 1,4-Dimethyl-7-propan-2-ylazulene
CAS No.: 489-84-9
EINECS: 207-701-2
RTECS: CO4790000
Molecular Formula: C₁₅H₁₈
Molecular Weight: 198.3 g/mol
Melting Point: 27-29 °C(lit.)
Density: 0.961 g/cm³
Flash Point: 142.3 °C
Boiling Point: 305.4 °C at 760 mmHg
Following is the structure of Guaiazulene (489-84-9):

Product Categories about Guaiazulene (489-84-9) are Azulenes ; Biochemistry ; Terpenes ; Terpenes (Others) ; Tropolones & Azulenes
The chemical synonymous of Guaiazulene (489-84-9) are 1,4-Dimethyl-7-(1-methylethyl)-azulen ; 1,4-Dimethyl-7-(1-methylethyl)azulene ; 1,4-Dimethyl-7-(1-methylethyl)-azulene ; 1,4-Dimethyl-7-isopropyl-azulen ; 3,8-Dimethyl-5-(2-propyl)azulene ; AZ-8 ; AZ-8 beris ; Azulen-Beris

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	525mg/kg (525mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 362, 1958.
mouse	LD50	oral	1220mg/kg (1220mg/kg)	BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 362, 1958.
rat	LD50	oral	1550mg/kg (1550mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 615, 1969.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:
Xn: Harmful
Risk Statements about Guaiazulene (489-84-9):
R22 Harmful if swallowed.
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements about Guaiazulene (489-84-9):
S22 Do not breathe dust.
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
Attentions:
1. Storage: Keep container closed when not in use. Refrigerator (approx 4 °C). Store in a cool, dry area away from incompatible substances.
2. Handling: Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Do not breathe dust. Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation