Name: 3,4-Dimethoxy-2-pyridinemethanol
SKU: 72830-08-1

Products Categories

Pharmaceutical (44)
Organic Chemicals (22)
Others (10)
Reagent (3)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	72830-08-1
Name:	3,4-Dimethoxy-2-pyridinemethanol
Article Data:	10

Formula:	C₈H₁₁NO₃
Molecular Weight:	169.18
Synonyms:	2-Hydroxymethyl-3,4-dimethoxypyridine;3,4-Dimethoxy-2-(hydroxymethyl)pyridine;
Density:	1.171 g/cm³
Boiling Point:	275.516 °C at 760 mmHg
Flash Point:	120.428 °C
Hazard Symbols:	Xi
PSA:	51.58000
LogP:	0.59110

Synthetic route

: 72830-07-0
3,4-dimethoxy-2-methylpyridine N-oxide

: 72830-08-1
2-hydroxymethyl-3,4-dimethoxypyridine

Conditions

Conditions	Yield
With acetic anhydride for 4h; Reflux;	91%
Stage #1: 3,4-dimethoxy-2-methylpyridine N-oxide With acetic anhydride at 90℃; for 2h; Stage #2: With sodium hydroxide In water at 80℃; for 2h;	76%
Multi-step reaction with 2 steps 1: 4 h / 100 °C 2: 2 M NaOH / 1 h / 100 °C View Scheme
Multi-step reaction with 2 steps 1: 2 h / 90 °C 2: 2 N aq. NaOH / 2 h / 80 °C View Scheme
Multi-step reaction with 2 steps 1: AcOH / 120 °C 2: 2N aq. NaOH / methanol / 2 h / 25 °C View Scheme

: 102625-99-0
2-acetoxymethyl-3,4-dimethoxypyridine

: 72830-08-1
2-hydroxymethyl-3,4-dimethoxypyridine

Conditions

Conditions	Yield
With sodium hydroxide at 80℃; for 2h; Yield given;
With sodium hydroxide In methanol at 25℃; for 2h;
With sodium hydroxide at 100℃; for 1h;
With sodium hydroxide In Petroleum ether
With sodium hydroxide In Petroleum ether

: 118-71-8
Maltol

: 72830-08-1
2-hydroxymethyl-3,4-dimethoxypyridine

Conditions

Conditions	Yield
Multi-step reaction with 7 steps 1: 68 percent / K2CO3 / acetone / 19 h / Heating 2: 77 percent / conc. ammonia / 3 h / 110 °C 3: 85 percent / POCl3 / 10 h / Heating 4: NaOMe / 10 h / Heating 5: 98 percent / 84percent m-CPBA / CH2Cl2 / 4 h / Ambient temperature 6: 4 h / 100 °C 7: 2 M NaOH / 1 h / 100 °C View Scheme
Multi-step reaction with 4 steps 1.1: ammonium hydroxide / 2 h / 40 °C 1.2: 10 h / 40 °C / Reflux 2.1: potassium hydroxide / water / 20 h / 10 - 20 °C 3.1: acetic acid; sodium tungstate; dihydrogen peroxide / 4 h / 40 - 95 °C 4.1: acetic anhydride / 4 h / Reflux View Scheme

: 4780-14-7
3-methoxy-2-methyl-4-pyrone

: 72830-08-1
2-hydroxymethyl-3,4-dimethoxypyridine

Conditions

Conditions	Yield
Multi-step reaction with 6 steps 1: 77 percent / conc. ammonia / 3 h / 110 °C 2: 85 percent / POCl3 / 10 h / Heating 3: NaOMe / 10 h / Heating 4: 98 percent / 84percent m-CPBA / CH2Cl2 / 4 h / Ambient temperature 5: 4 h / 100 °C 6: 2 M NaOH / 1 h / 100 °C View Scheme

: 76015-11-7
2-methyl-3-methoxy-4(1H)-pyridinone

: 72830-08-1
2-hydroxymethyl-3,4-dimethoxypyridine

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: 85 percent / POCl3 / 10 h / Heating 2: NaOMe / 10 h / Heating 3: 98 percent / 84percent m-CPBA / CH2Cl2 / 4 h / Ambient temperature 4: 4 h / 100 °C 5: 2 M NaOH / 1 h / 100 °C View Scheme
Multi-step reaction with 5 steps 1: 96 percent / POCl3 / 18 h / 90 °C 2: 90 percent / 30percent aq. H2O2, AcOH / 24 h / 90 °C 3: 91 percent / NaOMe / 18 h 4: 2 h / 90 °C 5: 2 N aq. NaOH / 2 h / 80 °C View Scheme
Multi-step reaction with 4 steps 1.1: trichlorophosphate / 18 h / 90 °C / Inert atmosphere 2.1: acetic acid; dihydrogen peroxide / water / 24 h / 90 °C 3.1: methanol / 16 h / 40 °C 4.1: acetic anhydride / 2 h / 90 °C 4.2: 2 h / 80 °C View Scheme

: 107512-34-5
4-Chloro-3-methoxy-2-methyl-pyridine

: 72830-08-1
2-hydroxymethyl-3,4-dimethoxypyridine

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: NaOMe / 10 h / Heating 2: 98 percent / 84percent m-CPBA / CH2Cl2 / 4 h / Ambient temperature 3: 4 h / 100 °C 4: 2 M NaOH / 1 h / 100 °C View Scheme
Multi-step reaction with 4 steps 1: 90 percent / 30percent aq. H2O2, AcOH / 24 h / 90 °C 2: 91 percent / NaOMe / 18 h 3: 2 h / 90 °C 4: 2 N aq. NaOH / 2 h / 80 °C View Scheme
Multi-step reaction with 3 steps 1.1: acetic acid; dihydrogen peroxide / water / 24 h / 90 °C 2.1: methanol / 16 h / 40 °C 3.1: acetic anhydride / 2 h / 90 °C 3.2: 2 h / 80 °C View Scheme

: 107512-35-6
3,4-dimethoxy-2-methylpyridine

: 72830-08-1
2-hydroxymethyl-3,4-dimethoxypyridine

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 98 percent / 84percent m-CPBA / CH2Cl2 / 4 h / Ambient temperature 2: 4 h / 100 °C 3: 2 M NaOH / 1 h / 100 °C View Scheme
Multi-step reaction with 2 steps 1: acetic acid; sodium tungstate; dihydrogen peroxide / 4 h / 40 - 95 °C 2: acetic anhydride / 4 h / Reflux View Scheme

: 15931-25-6
3-methoxy-2-methyl-4-nitropyridine 1-oxide

: 72830-08-1
2-hydroxymethyl-3,4-dimethoxypyridine

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 88 percent / NaOMe / 16 h / 40 °C 2: 2 h / 90 °C 3: 2 N aq. NaOH / 2 h / 80 °C View Scheme

: 35392-65-5
3-methoxy-2-methylpyridine 1-oxide

: 72830-08-1
2-hydroxymethyl-3,4-dimethoxypyridine

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 58 percent / 98percent HNO3 / acetic acid / 33 h / 80 °C 2: 88 percent / NaOMe / 16 h / 40 °C 3: 2 h / 90 °C 4: 2 N aq. NaOH / 2 h / 80 °C View Scheme

: 122307-41-9
4-chloro-3-methoxy-2-methylpyridine N-oxide

: 72830-08-1
2-hydroxymethyl-3,4-dimethoxypyridine

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 91 percent / NaOMe / 18 h 2: 2 h / 90 °C 3: 2 N aq. NaOH / 2 h / 80 °C View Scheme
Multi-step reaction with 2 steps 1.1: methanol / 16 h / 40 °C 2.1: acetic anhydride / 2 h / 90 °C 2.2: 2 h / 80 °C View Scheme

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:69 Page 1 of 2 1 2 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 72830-08-1

Chemistry

Product Name: 3,4-Dimethoxy-2-pyridinemethanol
Molecular Structure:

Molecular Formula: C₈H₁₁NO₃
Molecular Weight: 169.1778
Synonyms of 3,4-Dimethoxy-2-pyridinemethanol (CAS NO.72830-08-1): 4-Chloro-2-chloromethyl-3-methoxypyridine hydrochloride ; 4-Chloro-2-chloromethyl-3-methoxypyridine,hydrochloride salt ; 4-Chloro-3-methoxy-2-chloromethylpyridine hcl ; 4-Chloro-3-methoxy-2-chloromethyl pyridine hydrochloride ; 2-Hydroxymethyl-3,4-dimethoxypyridine
CAS NO: 72830-08-1
Product Categories: Pyridines, Pyrimidines, Purines and Pteredines ; Pyridines derivates ; API intermediates
H bond acceptors: 4
H bond donors: 1
Freely Rotating Bonds: 4
Polar Surface Area: 51.58 Å²
Index of Refraction: 1.523
Molar Refractivity: 44.152 cm³
Molar Volume: 144.478 cm³
Surface Tension: 42.229 dyne/cm
Density: 1.171 g/cm³
Flash Point: 120.428 °C
Enthalpy of Vaporization: 54.292 kJ/mol
Boiling Point: 275.516 °C at 760 mmHg
Vapour Pressure of 3,4-Dimethoxy-2-pyridinemethanol (CAS NO.72830-08-1): 0.002 mmHg at 25°C

Safety Profile

Hazard Codes of 3,4-Dimethoxy-2-pyridinemethanol (CAS NO.72830-08-1): Xi
Hazard Note: Irritant